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Thymectomy for Nonthymomatous Myasthenia Gravis: Comparison of Video-Assisted Thoracoscopic and Transsternal Thymectomy

Bagheri, R. and Boonstani, R. and Sadrizadeh, A. and Salehi, M. and Afghani, R. and Rahnama, A. and Azmounfar, V. and Hakimian, S. and Baradaran Firoozabadi, M. (2018) Thymectomy for Nonthymomatous Myasthenia Gravis: Comparison of Video-Assisted Thoracoscopic and Transsternal Thymectomy. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, 13 (2). pp. 77-80.

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Abstract

Objective: Thymectomy considered as a standard procedure in treatment of all the steps of myasthenia gravis. Video-assisted thoracoscopic surgery (VATS) thymectomy is one of the minimally invasive procedures that because of the short duration of hospitalization, less postoperative pain, and scar after surgery, nowadays it is replaced the traditional methods of surgery for patients with myasthenia gravis, but there are still differences and concerns. The aim of this study was to compare outcomes of two different techniques of surgery, VATS versus transsternal (TS) in the treatment of myasthenia gravis. Methods: In this pilot study, 42 patients with myasthenia gravis and without a thymus tumor were evaluated based on Myasthenia Gravis Foundation of America classification and drug consumption. Then, they randomly underwent two different techniques of surgery: VATS versus TS. Patients were evaluated based on preoperative and postoperative variables. Results: Duration of intensive care unit stay and hospitalization has been reduced in patients who underwent VATS thymectomy operation technique. In addition, duration of surgical procedure has been reduced significantly in these patients. These patients have less blood loss during surgery compared with TS group. The Myasthenia Gravis Foundation of America postoperative status in VATS thymectomy revealed that the number of patients with complete stable remission was higher and number of persons remained unchanged was lower in this group. Conclusions: VATS thymectomy is a safe and appropriate approach comparing with traditional methods such as TS thymectomy for patients with myasthenia gravis. This method has better results after surgery and can be used as a minimally invasive alternative method instead of TS thymectomy. Copyright © 2018 by the International Society for Minimally Invasive Cardiothoracic Surgery.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: cholinesterase inhibitor, adolescent; clinical article; comparative study; computer assisted tomography; Conference Paper; controlled study; disease classification; disease duration; drug use; female; hospitalization; human; intensive care unit; laboratory test; lung function test; male; myasthenia gravis; nonthymomatous myasthenia gravis; operation duration; outcome assessment; pilot study; postoperative hemorrhage; preoperative period; remission; thymectomy; transsternal thymectomy; video assisted thoracoscopic surgery
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: UNSPECIFIED
Depositing User: GOUMS
Date Deposited: 29 Sep 2018 07:39
Last Modified: 29 Sep 2018 07:39
URI: http://eprints.goums.ac.ir/id/eprint/9703

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