Golestan University of Medical Sciences Repository

Assessment of the prevalence of diabetic gastroparesis and validation of gastric emptying scintigraphy for diagnosis [Diyabetik Gastroparezi Prevalansı ve Tanısında Mide Boşalma Sintigrafisinin Geçerliliğinin Araştırılması]

Alipour, Z. and Khatib, F. and Tabib, S.M. and Javadi, H. and Jafari, E. and Aghaghazvini, L. and Mahmoud-Pashazadeh, A. and Nabipour, I. and Assadi, M. (2017) Assessment of the prevalence of diabetic gastroparesis and validation of gastric emptying scintigraphy for diagnosis [Diyabetik Gastroparezi Prevalansı ve Tanısında Mide Boşalma Sintigrafisinin Geçerliliğinin Araştırılması]. Molecular Imaging and Radionuclide Therapy, 26 (1). pp. 17-23.

Full text not available from this repository.

Abstract

Objective: Gastroparesis is defined as delayed gastric emptying and is a common medical condition in diabetic patients. Scintigraphy is commonly used as a standard diagnostic procedure for the quantitative assessment of gastroparesis. The aims of this study were to determine an optimum imaging time for the diagnosis of gastroparesis, to assess the prevalence of gastroparesis, to evaluate the correlation between endoscopy and scintigraphy findings as well as the correlation between gastric emptying with patient genders, blood glucose concentration, and functional dyspepsia. Methods: Gastric emptying was assessed in 50 diabetic patients with a mean age of 50.16 years. For evaluation of gastric emptying, a test meal containing 2 pieces of toast, 120 cc non-labeled water and fried egg labeled with 1 mCi of99mTc was given to each patient. The scintigraphy was performed immediately after ingestion and was repeated at 1, 1.5, 2 and 4 hours after ingestion. In some patients, an additional 90-minute dynamic scan was also acquired. Results: The prevalence of gastroparesis in this study population was determined as 64. Also, the results of this study revealed that a 4-hour scan after ingestion is more relevant than a 90-minute dynamic scan for the evaluation of delayed gastric emptying. There was no statistically significant difference between 1-hour and 2-hour scans, 1-hour and 90-minute scans, 2-hour and 90-minute scans, 2-hour and 4-hour scans. Likewise there was no significant correlation between blood glucose levels, gender and calculated values of gastric emptying time in all groups. Conclusion: According to our findings, it can be suggested that the prevalence of gastroparesis is higher than that mentioned in some previous studies. Also, this study indicates that a gastric emptying scintigraphy at 2 and 4 hours after meal ingestion might provide the anticipated clinical information in diabetic patients with dyspepsia without other evident reasons. © 2017 by Turkish Society of Nuclear Medicine.

Item Type: Article
Additional Information: cited By 0
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 09 Oct 2017 05:00
Last Modified: 09 Oct 2017 05:00
URI: http://eprints.goums.ac.ir/id/eprint/9466

Actions (login required)

View Item View Item