Golestan University of Medical Sciences Repository

Measurement and associative factors of adherence to epilepsy drug treatment among the elderly population in Tehran (Iran)

Fadaye-Vatan, R. and Delbari, A. and Lotfalinezhad, E. and Amini, F. and Gharagozli, K. and Bolhari, J. and Bahrami, P. and Saii, V. and Ahmadi, A. and Moghadam, Z. and Aflakseir, A. and Bhalla, D. (2017) Measurement and associative factors of adherence to epilepsy drug treatment among the elderly population in Tehran (Iran). International Journal of Epilepsy, 4 (1). pp. 46-50.

Full text not available from this repository.


Purpose The objective of this survey was to measure adherence and to identify correlation and prediction factors related to noncompliance among the elderly in Tehran, Iran. Methods A population-based survey was carried out among the elderly (≥60 years of age) by using Tehran Epilepsy registry. All subjects were contacted by telephone and invited for face-to-face consultation. Questionnaires used were the following: Medication Adherence Rating Scale (MARS); Medical Prescription Knowledge (MPK); Abbreviated Mental Test (AMT). Along with customary descriptive statistics, a simple chi-square test (or Fischer exact test if value of cells was ≤5) was used for correlating; Cramer's V was used for strength of association, and prediction was by logistic regression. Results Out of 104 subjects’ approached, 23 subjects (median age 62.0, 95% CI 61.0–64.7, range 60–71; 73.9% males; 78.3% married and having a living partner; 54.5% epilepsy as supernatural; 21.7% with comorbid condition) participated. Most did not have a recent epilepsy onset (n = 20, 86.8%), or had active epilepsy (n = 22, 95.7%), convulsive seizures (n = 21, 91.3%), with no (n = 13, 56.5%) to low seizure number, and polytherapy (n = 12, 52.2%). Median MARS score was 8.0 (95% CI 6.0–8.0, range 3–10). Nonadherence was correlated to comorbidity (p = 0.003) and widowhood or divorcehood (p = 0.04) and predicted by the same factors. Treatment side effects altered behavior (p = 0.03), and unsteadiness (p = 0.01) was also associated with nonadherence. MPK was positive for all participants. Median AMT score was 9.0 (95% CI 9.0–10.0, range 6–10). Conclusion Elderly patients had a high treatment adherence and, as logically expected, were associated with comorbid state, divorce-widowhood, and drug-related behavioral side effects particularly behavioral and unsteadiness. © 2016

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: acetazolamide; anticonvulsive agent; carbamazepine; clonazepam; lamotrigine; levetiracetam; oxcarbazepine; phenobarbital; phenytoin; primidone; valproic acid, Abbreviated Mental test; adult; aged; agitation; anxiety; Article; assessment of humans; attention disturbance; behavior disorder; clinical article; dermatitis; disease severity; divorce; dizziness; drowsiness; epilepsy; female; gingiva bleeding; hand tremor; headache; health survey; human; hyperactivity; Iran; irritability; loss of appetite; malaise; male; Medical Prescription Knowledge; Medication Adherence Rating scale; nausea; nervousness; patient compliance; priority journal; questionnaire; seizure; social status; unsteadiness; weight gain; weight reduction; xerostomia
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 08 Oct 2017 11:12
Last Modified: 08 Oct 2017 11:12
URI: http://eprints.goums.ac.ir/id/eprint/9424

Actions (login required)

View Item View Item