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Inoperable esophageal cancer and outcome of palliative care

Besharat, S. and Jabbari, A. and Semnani, S. and Keshtkar, A. and Marjani, J. (2008) Inoperable esophageal cancer and outcome of palliative care. World Journal of Gastroenterology, 14 (23). pp. 3725-3728.

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Abstract

Aim: To determine the outcome of esophageal cancer patients referred for palliative care, in Gorgan and Gonbad gastrointestinal clinics, northeast of Iran. Methods: This cross-sectional study was done on inoperable esophageal cancer cases referred to gastrointestinal clinics in Gorgan and Gonbad city (2005-2006). Demographic data were collected during the procedure and cases were followed up every one month. Improvement proportion was calculated with 95 confidence interval, to determine the rate of improvement. Survival analysis and Kaplan-Meier methods were used to estimate the duration of palliative care effectiveness. Results: We recruited 39 cases into the study. Squamous cell carcinoma was the most prevalent (92.3). The middle third of the esophagus was involved predominantly (51.3). Dilation was the most preferred method (89.7) and stenting was done in 4 cases. Decreasing dysphagia score was not related to palliation method or pathology type of carcinoma. Age of the patients was significantly related to the improvement of dysphagia score. Mean survival time was 137.6 d and median was 103 d. Conclusion: Results of this study showed a low survival rate after palliative care in esophageal cancer cases despite dysphagia scores' improvement after dilating or stenting. © 2008 The WJG Press. All rights reserved.

Item Type: Article
Additional Information: cited By 17
Uncontrolled Keywords: aged; article; cancer palliative therapy; cancer survival; clinical article; controlled study; cross-sectional study; dysphagia; esophageal adenocarcinoma; esophageal squamous cell carcinoma; esophagus cancer; esophagus dilatation; female; follow up; human; inoperable cancer; Iran; male; prevalence; scoring system; stent; survival rate; survival time; treatment response; tumor localization, Age Factors; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cross-Sectional Studies; Deglutition Disorders; Dilatation; Esophageal Neoplasms; Female; Humans; Iran; Kaplan-Meiers Estimate; Male; Middle Aged; Palliative Care; Quality of Life; Severity of Illness Index; Stents; Time Factors; Treatment Outcome
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: UNSPECIFIED
Depositing User: GOUMS
Date Deposited: 13 Aug 2017 02:51
Last Modified: 13 Aug 2017 02:51
URI: http://eprints.goums.ac.ir/id/eprint/9347

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