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Cruciate ligament reconstruction and risk of knee osteoarthritis: The association between cruciate ligament injury and post-traumatic osteoarthritis. a population based nationwide study in Sweden, 1987-2009

Nordenvall, R. and Bahmanyar, S. and Adami, J. and Mattila, V.M. and Felländer-Tsai, L. (2014) Cruciate ligament reconstruction and risk of knee osteoarthritis: The association between cruciate ligament injury and post-traumatic osteoarthritis. a population based nationwide study in Sweden, 1987-2009. PLoS ONE, 9 (8).

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Abstract

Objective: To study the association between Cruciate Ligament (CL) injury and development of post-traumatic osteoarthritis in the knee in patients treated operatively with CL reconstruction compared with patients treated non-operatively. Design: Population based cohort study; level of evidence II-2. Setting: Sweden, 1987-2009. Participants: All patients aged between 15-60 years being diagnosed and registered with a CL injury in The National Swedish Patient Register between 1987 and 2009. Main Outcome Measures: Knee osteoarthritis. Results: A total of 64,614 patients diagnosed with CL injury during 1987 to 2009 in Sweden were included in the study. Seven percent of the patients were diagnosed with knee OA in specialized healthcare during the follow-up (mean 9 years). Stratified analysis by follow-up showed that while those with shorter follow-up had a non-significant difference in risk (0.99, 95CI 0.90-1.09 for follow-up less than five years compared with the non-operated cohort), those with longer follow-up had an increased risk of knee OA after CL reconstruction (HR = 1.42, 95CI 1.27-1.58 for follow-up more than ten years compared with non-operated cohort). The risk to develop OA was not affected by sex. Conclusion: CL reconstructive surgery does not seem to have a protective effect on long term OA in either men or women. © 2014 Nordenvall et al.

Item Type: Article
Additional Information: cited By 12
Uncontrolled Keywords: adult; anterior cruciate ligament injury; anterior cruciate ligament reconstruction; article; cohort analysis; conservative treatment; disease association; female; follow up; human; knee osteoarthritis; major clinical study; male; middle aged; osteotomy; population research; posttraumatic arthropathy; risk assessment; sex difference; Sweden; total knee replacement; adolescent; adverse effects; anterior cruciate ligament; health survey; history; incidence; injuries; knee ligament; knee meniscus; Osteoarthritis, Knee; plastic surgery; postoperative complication; register; risk; surgery; young adult, Adolescent; Adult; Anterior Cruciate Ligament; Cohort Studies; Follow-Up Studies; History, 20th Century; History, 21st Century; Humans; Incidence; Menisci, Tibial; Middle Aged; Osteoarthritis, Knee; Population Surveillance; Posterior Cruciate Ligament; Postoperative Complications; Reconstructive Surgical Procedures; Registries; Risk; Sweden; Young Adult
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 25 Jul 2017 04:10
Last Modified: 25 Jul 2017 04:10
URI: http://eprints.goums.ac.ir/id/eprint/9311

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