Golestan University of Medical Sciences Repository

Dairy food intake and all-cause, cardiovascular disease, and cancer mortality: The Golestan Cohort Study

Farvid, M.S. and Malekshah, A.F. and Pourshams, A. and Poustchi, H. and Sepanlou, S.G. and Sharafkhah, M. and Khoshnia, M. and Farvid, M. and Abnet, C.C. and Kamangar, F. and Dawsey, S.M. and Brennan, P. and Pharoah, P.D. and Boffetta, P. and Willett, W.C. and Malekzadeh, R. (2017) Dairy food intake and all-cause, cardiovascular disease, and cancer mortality: The Golestan Cohort Study. American Journal of Epidemiology, 185 (8). pp. 697-711.

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We investigated the association between dairy product consumption and all-cause, cardiovascular disease (CVD), and cancer mortality in the Golestan Cohort Study, a prospective cohort study launched in January 2004 in Golestan Province, northeastern Iran. A total of 42,403 men and women participated in the study and completed a diet questionnaire at enrollment. Cox proportional hazards models were used to estimate hazard ratios and 95 confidence intervals. We documented 3,291 deaths (1,467 from CVD and 859 from cancer) during 11 years of follow-up (2004-2015). The highest quintile of total dairy product consumption (versus the lowest) was associated with 19 lower all-cause mortality risk (hazard ratio (HR) = 0.81, 95 confidence interval (CI): 0.72, 0.91; Ptrend = 0.006) and 28 lower CVD mortality risk (HR = 0.72, 95 CI: 0.60, 0.86; Ptrend = 0.005). High consumption of low-fat dairy food was associated with lower risk of all-cause (HR = 0.83, 95 CI: 0.73, 0.94; Ptrend = 0.002) and CVD (HR = 0.74, 95 CI: 0.61, 0.89; Ptrend = 0.001) mortality. We noted 11 lower all-cause mortality and 16 lower CVD mortality risk with high yogurt intake. Cheese intake was associated with 16 lower all-cause mortality and 26 lower CVD mortality risk. Higher intake of high-fat dairy food and milk was not associated with all-cause or CVD mortality. Neither intake of individual dairy products nor intake of total dairy products was significantly associated with overall cancer mortality. High consumption of dairy products, especially yogurt and cheese, may reduce the risk of overall and CVD mortality. © 2017 The Author.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: yoghurt, cancer; cardiovascular disease; cohort analysis; food consumption; food product; health risk; mortality; public health, adult; aged; Article; cancer mortality; cardiovascular disease; cheese; cohort analysis; dairy product; digestive system cancer; female; follow up; food intake; fruit; grain; human; Iran; major clinical study; male; milk; mortality risk; prospective study; questionnaire; red meat; vegetable, Golestan; Iran
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Depositing User: GOUMS
Date Deposited: 18 Jun 2017 19:34
Last Modified: 18 Jun 2017 19:34
URI: http://eprints.goums.ac.ir/id/eprint/5132

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