Golestan University of Medical Sciences Repository

Synthesis of pyrano2,3-cpyrazoles by ionic liquids under green and eco-safe conditions

Zakeri, M. and Nasef, M.M. and Kargaran, T. and Ahmad, A. and Abouzari-Lotf, E. and Asadi, J. (2017) Synthesis of pyrano2,3-cpyrazoles by ionic liquids under green and eco-safe conditions. Research on Chemical Intermediates, 43 (2). pp. 717-728.

Full text not available from this repository.


Optimization of a green approach to the synthesis of pyrano2,3-cpyrazoles based on the one-pot, four-component condensation via a domino Knoevenagel/Michael/cyclization sequence was investigated. This method involved the evaluation of the activity of several ionic liquids (ILs) in various solvents. This one-pot, four-component reaction revealed simplicity, higher yield and lower toxicity advantages over a corresponding three-component method. The effect of reaction parameters including the type and amount of catalyst, type of solvent, reaction temperature and time were studied with respect to yield of pyrano2,3-cpyrazoles. Catalyst recyclability and time-saving aspects of the reaction suggest that this method presents real alternatives over conventional reaction protocols. © 2016, Springer Science+Business Media Dordrecht.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: Catalysts; Liquids, Catalyst recyclability; Green chemistry; Ionic liquid (ils); Pyrazoles; Pyrazolones; Reaction parameters; Reaction protocols; Reaction temperature, Ionic liquids
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Depositing User: GOUMS
Date Deposited: 18 Jun 2017 16:58
Last Modified: 18 Jun 2017 16:58
URI: http://eprints.goums.ac.ir/id/eprint/5105

Actions (login required)

View Item View Item