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Effect of antimicrobial photodynamic therapy on the counts of salivary Streptococcus mutans in children with severe early childhood caries

Fekrazad, R. and Seraj, B. and Chiniforush, N. and Rokouei, M. and Mousavi, N. and Ghadimi, S. (2017) Effect of antimicrobial photodynamic therapy on the counts of salivary Streptococcus mutans in children with severe early childhood caries. Photodiagnosis and Photodynamic Therapy, 18. pp. 319-322.

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Abstract

Background Antimicrobial photodynamic therapy (aPDT) is a novel technique for reduction of pathogenic microorganisms in dentistry. The aim of this study was to evaluate the effects of aPDT on Streptococcus mutans reduction in children with severe early childhood caries. Methods Twenty-two children with severe early childhood caries aged 3–6 years were treated with toluoidine blue O (TBO) for 1 min and irradiated by a Light Emitting Diode (LED; FotoSan, CMS Dental, Denmark) with the exposure time of 150 s. Saliva samples were collected at baseline, 1 h and 7 days after treatment. S. mutans counts were determined using the Dentocult SM Strip mutans. Results The counts of S. mutans in saliva decreased significantly after 1 h (P < 0.001). However, the difference in reduction of S. mutans counts in saliva was not significant between the baseline and 7 days after treatment (P > 0.05). Conclusion aPDT seems to be efficient to reduce salivary S. mutans immediately after treatment in children with severe early childhood caries. However, further research is needed to evaluate different doses and frequency of irradiation in combination with restoring carious teeth to find more durable results. © 2017 Elsevier B.V.

Item Type: Article
Additional Information: cited By 0
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: UNSPECIFIED
Depositing User: GOUMS
Date Deposited: 18 Jun 2017 15:06
Last Modified: 18 Jun 2017 15:06
URI: http://eprints.goums.ac.ir/id/eprint/5059

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