Golestan University of Medical Sciences Repository

Antioxidant activity of different fractions of methanolic extract of the golden chanterelle mushroom Cantharellus cibarius (higher basidiomycetes) from Iran

Ebrahimzadeh, M.A. and Safdari, Y. and Khalili, M. (2015) Antioxidant activity of different fractions of methanolic extract of the golden chanterelle mushroom Cantharellus cibarius (higher basidiomycetes) from Iran. International Journal of Medicinal Mushrooms, 17 (6). pp. 557-565.

Full text not available from this repository.


Natural compounds with antioxidant activity can be useful for treatment of reactive oxygen species-related diseases, comprising atherosclerosis, inflammatory injury, cardiovascular disease, cancer, diabetes, Alzheimer's disease, cataracts, autism, and aging. The current study was perform to assay the antioxidant activity different fractions of methanolic extract of golden chanterelle mushroom Cantharellus cibarius, a mushroom found in the north of Iran. Different fractions of methanolic extract of this mushroom, including n-hexane, chloroform, ethyl acetate, n-butanol, and water, were evaluated for antioxidant activity using six in vitro assay systems. Mushroom fruit was obtained from the local market, Sari (northern Iran). The n-hexane fraction had higher amounts of flavonoids contents (40.01 ± 1.30 mg quercetin equivalent g−1 of extract) and the highest exhibition of nitric oxide scavenging activity (77.21 ± 1.48%). The highest content of phenol was observed in the n-butanol fraction, which was 40.97 ± 0.99 mg gallic acid equivalent g−1 of extract. Among all the fractions, the ethyl acetate fraction was found to show higher DPPH scavenging activity (33.43 ± 1.30%) and the aqueous fraction to display the most reducing power. The highest Fe2+ chelating activity was observed in the chloroform fraction and then in the n-hexane fraction (86.13 ± 1.61 and 80.68 ± 2.07, respectively). The results all together signify C. cibarius as a valuable source of natural bioactive compounds with antioxidant activity. © 2015 Begell House, Inc.

Item Type: Article
Additional Information: cited By 1
Uncontrolled Keywords: acetic acid ethyl ester; butanol; Cantharellus cibarius extract; chloroform; ferrous ion; flavonoid; fungal extract; gallic acid; hexane; nitric oxide; phenol derivative; unclassified drug; water; antioxidant; biological product; chelating agent; reducing agent; scavenger, antioxidant activity; Article; Cantharellus cibarius; chelation; DPPH radical scavenging assay; Iran; nonhuman; Agaricales; chemistry; human; isolation and purification, Basidiomycota; Cantharellus cibarius, Agaricales; Antioxidants; Biological Products; Chelating Agents; Free Radical Scavengers; Humans; Iran; Reducing Agents
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 10 Sep 2016 08:15
Last Modified: 10 Sep 2016 08:15
URI: http://eprints.goums.ac.ir/id/eprint/4791

Actions (login required)

View Item View Item