Golestan University of Medical Sciences Repository

Association between trace elements and metabolic syndrome among type 2 diabetes mellitus patients in gorgan

Marjani, A. and Akbari, F.A. and Eshghinia, S. (2015) Association between trace elements and metabolic syndrome among type 2 diabetes mellitus patients in gorgan. Asian Journal of Pharmaceutical and Clinical Research, 8 (3). pp. 358-362.

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Abstract

Objective: Metabolic syndrome changes in different ethnic and age group. Trace elements are associated with metabolic syndrome. The present study was aimed to assess the serum levels of Iron, zinc and copper in Gorgan and their association with the metabolic syndrome components. Methods: The present study was carried out in the Metabolic Disorders Research Center of Gorgan Faculty of Medicine. There were one hundred and fifty two type 2 diabetic subjects who were referred to the Department of Diabetes Center in 5th Azar Educational Hospital in Golestan University of Medical Sciences, Iran, 2014. Results: The mean waist circumference, systolic and diastolic blood pressure, total cholesterol, triglyceride and fasting blood glucose levels were significantly higher in the Type 2 diabetic patients with metabolic syndrome, but the mean HDL-cholesterol was significantly lower (P<0.05). Mean serum level of copper was slightly higher and mean serum level of zinc and iron were lower in patients with metabolic syndrome than that of subjects without metabolic syndrome. There were significant differences in the mean of systolic and diastolic blood pressure, triglyceride, HDL-cholesterol and fasting blood glucose in men and women with metabolic syndrome when compared with subjects without metabolic syndrome. There were also significant differences in the mean of BMI and waist circumference in women with metabolic syndrome. Serum zinc positively correlated with HDL-cholesterol level (in all and in women type 2 diabetic patients), systolic blood pressure (in all type 2 diabetic patients) and diastolic blood pressure (in men type 2 diabetic patients) (P<0.05). Conclusion: Differences of our results with other studies emphasize further research on trace elements and metabolic syndrome and their relationship with different diseases are necessary. © 2015 Asian Journal of Pharmaceutical and Clinical Research. All rights reserved.

Item Type: Article
Additional Information: cited By 0
Uncontrolled Keywords: cholesterol; copper; glucose; high density lipoprotein cholesterol; iron; triacylglycerol; zinc, adult; Article; body mass; cholesterol blood level; controlled study; copper blood level; diastolic blood pressure; disease association; female; glucose blood level; human; Iran; iron blood level; major clinical study; male; metabolic syndrome X; middle aged; non insulin dependent diabetes mellitus; obesity; systolic blood pressure; triacylglycerol blood level; waist circumference; zinc blood level
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 10 Sep 2016 05:10
Last Modified: 24 Dec 2016 08:31
URI: http://eprints.goums.ac.ir/id/eprint/4701

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