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The assessment of association of dipyridamole side effects with hemodynamic parameters, ECG and scintigraphy outcomes

Javadi, H. and Shariati, M. and Mogharrabi, M. and Asli, I.Neshandar and Hooman, A. and Jallalat, S. and Assadi, M. (2010) The assessment of association of dipyridamole side effects with hemodynamic parameters, ECG and scintigraphy outcomes. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 37 (2). S375.

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Abstract

Aim: Dipyridamole has extensively been administered to simulate physical activity in cardiovascular assessment. The aim of this study was to assess the association of dipyridamole side effects with hemodynamic oscillations, scanning results and ECG findings. Materials & Methods: Overlay, 590 cases referred to nuclear medicine center for myocardial perfusion imaging were evaluated for the adverse effects of dipyridamole concurrent with low level of exercise. Before and during dipyridamole infusion, the patients' vital symptoms, electrocardiogram, hear rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP) were monitored; all patients underwent stress/rest 99mTc‐sestamibi GSPECT using a 2‐day protocol. Results: Eighty‐eight patients (14.9%) showed at least one sort of undesired symptom during dipyridamole infusion; abnormal ECG and scan was observed in 32.3% and 48.6% of cases, respectively. There were significant differences between pre and post‐infusion HR, pre‐infusion SBP and post‐infusion DBP among patients with or without untoward symptoms; whereas no significant difference was observed in any of the hemodynamic parameters between patients with normal and abnormal ECG or myocardial perfusion imaging. Conclusion: This study demonstrated a correlation between hemodynamic variables and patients’ undesired symptoms but not with either imaging findings or ECG.

Item Type: Article
Additional Information: 23rd Annual Congress of the European-Association-of-Nuclear-Medicine (EANM), Vienna, AUSTRIA, OCT 09-13, 2010
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 27 Apr 2015 10:10
Last Modified: 20 Jun 2017 07:24
URI: http://eprints.goums.ac.ir/id/eprint/3995

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