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Diabetes mellitus and its correlates in an iranian adult population

Golozar, A. and Khademi, H. and Kamangar, F. and Poutschi, H. and Islami, F. and Abnet, C.C. and Freedman, N.D. and Taylor, P.R. and Pharoah, P. and Boffetta, P. and Brennan, P. and Dawsey, S.M. and Malekzadeh, R. and Etemadi, A. (2011) Diabetes mellitus and its correlates in an iranian adult population. PLoS ONE, 6 (10).

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Abstract

The rising epidemic of diabetes imposes a substantial economic burden on the Middle East. Using baseline data from a population based cohort study, we aimed to identify the correlates of diabetes mellitus (DM) in a mainly rural population from Iran. Between 2004 and 2007, 50044 adults between 30 and 87 years old from Golestan Province located in Northeast Iran were enrolled in the Golestan Cohort Study. Demographic and health-related information was collected using questionnaires. Individuals' body sizes at ages 15 and 30 were assessed by validated pictograms ranging from 1 (very lean) to 7 in men and 9 in women. DM diagnosis was based on the self-report of a physician's diagnosis. The accuracy of self-reported DM was evaluated in a subcohort of 3811 individuals using fasting plasma glucose level and medical records. Poisson regression with robust variance estimator was used to estimate prevalence ratios (PR's). The prevalence of self-reported DM standardized to the national and world population was 5.7 and 6.2, respectively. Self-reported DM had 61.5 sensitivity and 97.6 specificity. Socioeconomic status was inversely associated with DM prevalence. Green tea and opium consumption increased the prevalence of DM. Obesity at all ages and extreme leanness in childhood increased diabetes prevalence. Being obese throughout life doubled DM prevalence in women (PR: 2.1; 95 CI: 1.8, 2.4). These findings emphasize the importance of improving DM awareness, improving general living conditions, and early lifestyle modifications in diabetes prevention.

Item Type: Article
Additional Information: cited By 13
Uncontrolled Keywords: glucose; opiate, adolescent; adult; aged; article; body size; childhood; cohort analysis; controlled study; correlation analysis; diabetes mellitus; diagnostic accuracy; female; glucose blood level; human; Iran; major clinical study; male; medical information; medical record; obesity; population research; prevalence; questionnaire; rural area; self report; sensitivity and specificity; social status; standardization; tea; validation study; body mass; confidence interval; demography; diabetes mellitus; Iran; middle aged; waist circumference, Adult; Aged; Aged, 80 and over; Body Mass Index; Body Size; Cohort Studies; Confidence Intervals; Demography; Diabetes Mellitus; Female; Humans; Iran; Male; Middle Aged; Prevalence; Self Report; Waist Circumference
Subjects: کهورت
مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 21 Apr 2015 03:58
Last Modified: 19 May 2015 04:05
URI: http://eprints.goums.ac.ir/id/eprint/2580

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