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Reliability and validity of opiate use self-report in a population at high risk for esophageal cancer in Golestan, Iran

Abnet, C.C. and Saadatian-Elahi, M. and Pourshams, A. and Boffetta, P. and Feizzadeh, A. and Brennan, P. and Taylor, P.R. and Kamangar, F. and Dawsey, S.M. and Malekzadeh, R. (2004) Reliability and validity of opiate use self-report in a population at high risk for esophageal cancer in Golestan, Iran. Cancer Epidemiology Biomarkers and Prevention, 13 (6). pp. 1068-1070. ISSN 10559965

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Objective: To assess the reliability and validity of self-reported opium use in a rural Iranian population at high risk for esophageal cancer in preparation for a large cohort study. Method: 1,057 subjects ages 33 to 84 years were recruited from Gonbad city and three surrounding villages in Golestan province of Iran and completed a questionnaire and provided biological samples. The history and duration of using opium, smoking tobacco, chewing nass, and drinking alcohol were measured by questionnaire in the entire cohort. A subgroup of 130 people was reinterviewed after 2 months to assess reliability. Validity of the opium question was assessed by comparing the questionnaire responses with the presence of codeine and morphine in the urine of 150 selected subjects. Results: Self-reported opiate use is reliable and valid in this population. The reliability of ever opium use and duration of opium use had κ′s of 0.96 and 0.74, respectively. The validity of self-reported opium use was also high. Using urine codeine or morphine as the gold standard for use of opium, self-report had a sensitivity of 0.93 and a specificity of 0.89. Conclusions: The self-reported use of opium can provide a reliable and valid measurement in this population and will be useful for studying associations between opium use and occurrence of esophageal cancer and other diseases.

Item Type: Article
Additional Information: cited By 46
Uncontrolled Keywords: alcohol; illicit drug; opiate, adult; aged; alcohol consumption; article; cancer risk; cigarette smoking; drug urine level; drug use; esophagus cancer; esophagus disease; ethnic group; female; gas chromatography; high risk population; human; Iran; major clinical study; male; mass spectrometry; priority journal; reliability; self report; tobacco, Adult; Aged; Aged, 80 and over; Alcohol Drinking; Analgesics, Opioid; Codeine; Esophageal Neoplasms; Female; Follow-Up Studies; Humans; Iran; Male; Middle Aged; Morphine; Neoplasms, Squamous Cell; Opioid-Related Disorders; Opium; Pilot Projects; Questionnaires; Risk Factors; Rural Health; Self Disclosure; Smoking; Substance Abuse Detection
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 19 Apr 2015 10:16
Last Modified: 16 Apr 2018 08:57
URI: http://eprints.goums.ac.ir/id/eprint/2549

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