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Effect of Achillea santolina on mice spermatogenesis

Golalipour, M.J. and Khori, V. and Azarhoush, R. and Nayebpour, M. and Azadbakht, M. (2004) Effect of Achillea santolina on mice spermatogenesis. Daru, 12 (1). pp. 36-39. ISSN 15608115 (ISSN)

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Abstract

Achillea santolina, a common variety of Achillea in Golestan province of Iran has been used in traditional medicine for its anti - inflammatory properties. The effect of hydroalcoholic extract (300 mg/kg/day Intraperitoneally, for 20 days) of Achillea santolina on the spermatogenesis of mice was studied by the evaluation of morphologic characteristics by light microscope. The alterations observed were disorganized germ epithelium, exfoliation of immature germ cells, germ cell necrosis and increased number of metaphasfis in germinal epithelium of seminiferous tubules. We concluded that hydroalcoholic extract of Achillea santolina 300 mg/kg/day intraperitoneally for 20 days as a different variety of Achillea has antispermatogenic effect similar to Achillea millefolium on mice.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Daru [Field not mapped to EPrints] AD - Department of Anatomy, Golestan Univ. of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Pharmacology, Golestan Univ. of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Pathology, Golestan Univ. of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Pharmacology, Tehran Univ. of Medical Science, Tehran, Iran [Field not mapped to EPrints] AD - Department of Pharmacology, Mazandran Univ. of Med. Sci. Sari, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Achillea santolina, Mice, Spermatogenesis, achillea santolina extract, plant extract, unclassified drug, Achillea, animal experiment, animal tissue, article, controlled study, germ cell, histology, male, microscopy, morphology, mouse, nonhuman, seminiferous tubule, spermatogenesis
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 18 Apr 2015 03:43
Last Modified: 04 Feb 2017 09:45
URI: http://eprints.goums.ac.ir/id/eprint/2469

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