Golestan University of Medical Sciences Repository

Antibacterial activity of certain Iranian medicinal plants against methicillin-resistant and sensitive Staphylococcus aureus

Dadgar, T. and Asmar, M. and Saifi, A. and Mazandarani, M. and Bayat, H. and Moradi, A. and Bazueri, M. and Ghaemi, E. (2006) Antibacterial activity of certain Iranian medicinal plants against methicillin-resistant and sensitive Staphylococcus aureus. Asian Journal of Plant Sciences, 5 (5). pp. 861-866. ISSN 16823974 (ISSN)

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Abstract

Bacterial resistance to antibiotics is a serious global problem and includes strains of beta-lactam-resistant Staphylococcus aureus and methicillin-resistant S. aureus (MRSA). Novel antimicrobials and/or new approaches to combat the problem are urgently needed. The aim of this study was to investigate the antimicrobial activity of alcoholic and aqueous extract of 23 medical plants species of Golestan province on clinical and standard stains of MRSA and MSSA. Twenty three medicinal plants were collected from their natural habitat in Golestan province in north of Iran. Their ethanolic and aqueous extract obtained by percolation methods. Antibacterial effects were assessed by disk diffusion method and the Minimum Inhibitory Concentration (MIC) of the extracts was determined by the micro broth dilution against 14 clinical and standard strains of methicillin resistant and sensitive of Staphylococcus aureus. The ethanolic and aqueous extract of 8, 3 plants showed best anti staphylococcal effect, respectively. The ethanolic extract of Artemisia, herbaalba, Nigella sativa, Punica granatum, possed the most outstanding in vitro antibacterial activity which the maximum inhibition zone was 22.4-18 mm, respectively and the lowest MIC values was measured in Punica granatum, as 0.01 mg mL-1 against MRSA The results showed that ethanolic extract had better antibacterial effect than aqueous extract and anti staphylococcal activity of Ethanolic extract of plants against MRSA was better than MSSA strains. Ethanolic and aqueous extract of Punica granatum had the best antibacterial activity against the tested microorganisms. The result obtained from these plants might be considered sufficient for further studies. © 2006 Asian Network for Scientific Information.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Asian J. Plant Sci. [Field not mapped to EPrints] AD - Department of Microbiology, Golestan University of Medical Sciences, Iran [Field not mapped to EPrints] AD - Department of Microbiology, Lahijan Azad University, Iran [Field not mapped to EPrints] AD - Department of Plant Biology, Gorgan Azad University, Iran [Field not mapped to EPrints] AD - Niak Cytopharma Laboratory, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Antibacterial effect, Ethanolic and aqueous extract, Medicinal plant, Staphylococcus aureus, Artemisia, Bacteria (microorganisms), Lythraceae, methicillin resistant Staphylococcus aureus, Nigella sativa, Punica granatum, Staphylococcus aureus
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 15 Apr 2015 09:12
Last Modified: 06 Feb 2017 06:48
URI: http://eprints.goums.ac.ir/id/eprint/2437

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