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Epidemiological study of drug intoxication in children

Cheraghali, F. and Taymori, M. (2006) Epidemiological study of drug intoxication in children. Acta Medica Iranica, 44 (1). pp. 37-40. ISSN 00446025 (ISSN)

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Unintentional drug intoxication is still a major cause of morbidity and mortality in young children. In order to study the epidemiological pattern of childhood drug poisoning in Golestan province, all cases diagnosed with poisoning from 1997 to 2002 in the only pediatric hospital in province were recruited. During this period 563 cases of poisoned children were hospitalized in Taleqani hospital, of these 305 cases were due to drug poisoning. Opium was responsible for more than half of the poisoning cases, and 91% of deaths, among drug intoxicated children. Metoclopramide, benzodiazepines, tricyclic antidepressants and anticonvulsants were among the other frequent causes of poisoning. Neurological symptoms were the most prominent symptoms of poisoning and more than 80% of cases showed some neurological symptoms. Mortality rate among the cases was 3.6% and of total of 11 deaths, 10 were poisoned with opium. About 61% of cases were hospitalized between 24-48 hrs. Most of the poisoning cases in young children were unintentional and in many cases, their parents played a critical role in their intoxication. This role specially is crucial in infants and children under one year of age. Parents in Golestan province use opium widely for symptomatic treatment of routine illnesses in their young children and overdose of opium may cause severe intoxication and even death of the child. © 2006 Tehran University of Medical Sciences. All rights reserved.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Acta Med. Iran. [Field not mapped to EPrints] AD - Department of Pediatrics, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Children, Drug poisoning, Opium, anticonvulsive agent, benzodiazepine derivative, diazepam, gastrointestinal agent, histamine H2 receptor antagonist, imipramine, metoclopramide, opiate, phenobarbital, propranolol, tricyclic antidepressant agent, adolescent, article, child, childhood mortality, controlled study, drowsiness, drug intoxication, epidemiological data, extrapyramidal symptom, female, hospitalization, human, infant, Iran, major clinical study, male, neurologic disease, parental behavior, pediatric hospital, respiratory distress, sedation, vomiting
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 19 Apr 2015 04:25
Last Modified: 07 Feb 2017 09:19
URI: http://eprints.goums.ac.ir/id/eprint/2424

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