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Evaluation of post operative analgesic efficacy of intramuscular pethidine, compared to indometacin and diclofenac Na suppositories in unilateral inguinal hernioplasty patients

Arya, B. and Abdollahi, A.A. and Golalipour, M.J. and Kazemnezhad, K. and Mohammadi, M.R. (2007) Evaluation of post operative analgesic efficacy of intramuscular pethidine, compared to indometacin and diclofenac Na suppositories in unilateral inguinal hernioplasty patients. Journal of Medical Sciences, 7 (2). pp. 311-314. ISSN 16824474 (ISSN)

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Abstract

We compared analgesic effects of intramuscular pethidine to diclofenac sodium and indometacin suppositories. This study is a semiexperimental clinical trial study over 55 patients of 17 to 60 years old who had undergone unilateral inguinal hernioplasty. These patients divided into 3 groups incidentally the first group including 17 patients who received 100 mg indometacin suppository every 8 h to relief postoperative pain. The second group of 18 patients who received 100 mg Diclofenac Na suppository every 8 h and the third group including 20 patients who received 0.5 mg kg-1 body weight pethidine intramuscularly every 8 h and the first dose of each drug started 2 h after termination of operation. The severity of pain was checked by Visual Analogue Scale (VSA) method every 2 h for 24 h. Mean pain severity checked and compared in 6 h intervals. Mean pain severity and standard deviation in the first 24 h were 23±12 for indometacin and 27±12 for pethidine and 31±9 for diclofenac Na groups respectively. There is no meaningful difference in pain relief during the first post op day. We concluded that Indometacin and diclofenac Na suppositories are good substitutes of intramuscular pethidine to relief post op pain during the first post op day.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - J. Med. Sci. (Pakistan) [Field not mapped to EPrints] AD - Department of General Surgery, Golestan University of Medical Sciences, Iran [Field not mapped to EPrints] AD - Department of Nursing, Golestan University of Medical Sciences, Iran [Field not mapped to EPrints] AD - Department of Embryology, Golestan University of Medical Sciences, Iran [Field not mapped to EPrints] AD - Department of Anesthesiology, Golestan University of Medical Sciences, Iran [Field not mapped to EPrints] AD - Department of Neurosurgery, Golestan University of Medical Sciences, Iran [Field not mapped to EPrints] AD - Department of Surgery, 5th Azar Hospital, Gorgan University of Medical Sciences, P.O. Box 49175-553, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Diclofenac Na, Indometacin, Intramuscular pethidine, Nonsteroidal anti inflammatory drugs NSAID, Post operative (post op) pain, Suppository, diclofenac, indometacin, pethidine, adolescent, adult, analgesia, analgesic activity, article, clinical trial, comparative study, controlled clinical trial, controlled study, disease severity, drug efficacy, female, hernioplasty, human, inguinal hernia, major clinical study, male, pain assessment, postoperative care, postoperative pain, suppository, visual analog scale
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 19 Apr 2015 04:18
Last Modified: 13 Feb 2017 07:11
URI: http://eprints.goums.ac.ir/id/eprint/2409

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