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Efficacy of DOTS strategy in treatment of respiratory tuberculosis in Gorgan, Islamic Republic of Iran

Abassi, A. and Mansourian, A.R. (2007) Efficacy of DOTS strategy in treatment of respiratory tuberculosis in Gorgan, Islamic Republic of Iran. Eastern Mediterranean Health Journal, 13 (3). pp. 664-669. ISSN 10203397 (ISSN)

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Abstract

We carried out a follow-up cohort study of 260 smear-positive patients (178 on directly observed treatment, short-course (DOTS); 82 on non-DOTS] over a 2-year period to evaluate the efficacy of the DOTS strategy in treatment of tuberculosis (TB). All the patients had had cough for > 3 weeks; 91.9% had fever, 60.8% of them with sputum; and 27.7% had a positive family history. The rate of treatment failure with DOTS was 9.0% at the end of the 2nd month and 1.7% at the beginning of the 5th month. In the control group these rates were 18.3% and 7.3% respectively. The DOTS strategy significantly increased the success rate of TB treatment (P < 0.05).

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - East. Mediterr. Health J. [Field not mapped to EPrints] C2 - 17687840 [Field not mapped to EPrints] AD - Department of Infectious Diseases, Gorgan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Biochemistry, Gorgan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: ethambutol, isoniazid, pyrazinamide, rifampicin, adolescent, adult, article, clinical effectiveness, clinical protocol, clinical trial, cohort analysis, controlled clinical trial, controlled study, coughing, disease duration, drug safety, drug treatment failure, family history, female, fever, follow up, hemoptysis, human, Iran, lung tuberculosis, major clinical study, male, outcome assessment, short course therapy, sputum smear, tuberculosis control, Adolescent, Adult, Antitubercular Agents, Cough, Directly Observed Therapy, Drug Therapy, Combination, Ethambutol, Female, Fever, Follow-Up Studies, Hemoptysis, Humans, Incidence, Iran, Isoniazid, Male, Prevalence, Pyrazinamide, Rifampin, Rural Health, Sputum, Treatment Failure, Tuberculosis, Pulmonary, Urban Health
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 18 Apr 2015 03:51
Last Modified: 11 Feb 2017 04:53
URI: http://eprints.goums.ac.ir/id/eprint/2394

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