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Prevalence of hepatitis D virus infection in HBsAg positive subjects in Iran

Roshandel, G. and Semnani, S. and Abdolahi, N. and Keshtkar, A.A. and Besharat, S. and Joshaghani, H. and Moradi, A. and Kalavi, K. and Jabbari, A. and Kabir, M.J. and Hosseini, S.A. and Sedaqat, S.M. and Danesh, A. and Roshandel, D. and Hedayat-Mofidi, S.M. (2007) Prevalence of hepatitis D virus infection in HBsAg positive subjects in Iran. Pakistan Journal of Biological Sciences, 10 (10). pp. 1751-1754. ISSN 10288880 (ISSN)

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Abstract

Abstract This study was carried out to determine the seroprevalence of hepatitis D virus among HBsAg positive individuals in the northeast part of Iran. One hundred thirty nine HBsAg positive subjects detected from a population based single stage cluster sampling in Golestan province of Iran were enrolled. All cases were evaluated for the presence of anti-HDV antibodies using commercially available ELISA kits. Logistic regression was used to determine the relationship between independent variables and HDV seropositivity. Of 139 cases, 68(48.9%) were males and 71(51.1%) were females. The mean age was 41.89±11.30 years (25-64 years). Anti-HDV antibody was positive in 8 (5.8%) subjects with female predominance (9.9% versus 1.5%, p = 0.06; odds ratio = 7.32, 95%CI: 0.87-61.23). No significant relationship was seen between anti-HDV seropositivity and demographic factors such as age, place of residence and marital status. These findings showed that HDV infection was endemic in Golestan province (northeast) of Iran. Seroprevalence of Anti-HDV in the present study was higher than some previous studies from other parts of Iran. Our results suggest that the prevalence of HBV/HDV co-infection in Iran has increased during the last decade. Therefore, practitioners and all health care managers should be made aware of the risk of dual infection with HBV and HDV. © 2007 Asian Network for Scientific Information.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Pak. J. Biol. Sci. [Field not mapped to EPrints] C2 - 19086531 [Field not mapped to EPrints] AD - Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Golestan Province, Iran [Field not mapped to EPrints] AD - Faculty of Paramedicine, Golestan University of Medical Sciences, Golestan Province, Iran [Field not mapped to EPrints] AD - Department of Health, Golestan University of Medical Sciences, Golestan Province, Iran [Field not mapped to EPrints] AD - No. 77, Q. Passage, Valiasr St., Gorgan, Golestan Prov., 49166-53588, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Hepatitis B, Hepatitis D, Iran, hepatitis B surface antigen, adult, article, blood, cross-sectional study, delta agent hepatitis, enzyme linked immunosorbent assay, female, human, immunology, Iran, male, middle aged, prevalence, statistical model, Adult, Cross-Sectional Studies, Enzyme-Linked Immunosorbent Assay, Female, Hepatitis B Surface Antigens, Hepatitis D, Humans, Iran, Logistic Models, Male, Middle Aged, Prevalence, Hepatitis B virus, Hepatitis delta virus
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 20 Apr 2015 03:46
Last Modified: 15 Feb 2017 07:37
URI: http://eprints.goums.ac.ir/id/eprint/2393

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