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The effect of spatial learning on the number of astrocytes in rat dentate gyrus

Jahanshahi, M. and Sadeghi, Y. and Hosseini, A. and Naghdi, N. (2007) The effect of spatial learning on the number of astrocytes in rat dentate gyrus. Neuroanatomy, 6. pp. 51-53. ISSN 13031783 (ISSN)

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Abstract

In this study, we evaluated the effect of spatial learning on the number of astrocytes in the rat dentate gyrus with Morris water maze. Fifteen male albino Wistar rats were divided into three groups as control, reference memory and working memory groups. Each group was consisted of 5 rats. After spatial learning, the brains were histologically examined; the slides were stained with phosphotungstic acid hematoxylin (PTAH) staining to show the astrocytes. We found significant difference in the number of astrocytes in dentate gyrus between control and reference memory groups, and between control and working memory groups as well. When compared two learning groups there was a significant difference in the number of astrocytes between them, being higher in the working memory group. We concluded that the number of astrocytes increased due to spatial learning and this increase can be affected to the period of learning. Our studies of spatial learning and effect of learning techniques (reference and working memory) showed that the technique that has longer period of learning has more effect on the number of astrocytes.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Neuroanatomy [Field not mapped to EPrints] AD - Department of Anatomy, Faculty of Medicine, Gorgan University of Medical Sciences, Km 4 Gorgan - Suri Road, Gorgan, Iran [Field not mapped to EPrints] AD - Cellular and Molecular Research Center, Sirahid Bebeshil University of Medical Sciences, Tehran, Iran [Field not mapped to EPrints] AD - Department of Physiology, Institute of Pasteur, Tehran, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Astrocyte, Dentate gyrus, PTAS steining, Spatial learning, animal cell, animal experiment, article, astrocyte, cell count, controlled study, dentate gyrus, hippocampus, histology, learning, male, maze test, nonhuman, rat, reference memory, spatial memory, working memory
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 19 Apr 2015 05:44
Last Modified: 18 Feb 2017 05:14
URI: http://eprints.goums.ac.ir/id/eprint/2355

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