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Prevalence of HTLV-1 antibody among major thalassemic patients in Gorgan (South East of Caspian Sea)

Moradi, A. and Mansurian, A.R. and Ahmadi, A.R. and Ghaemi, E. and Kalavi, K.H. and Marjani, A. and Moghaddam, E.S. (2008) Prevalence of HTLV-1 antibody among major thalassemic patients in Gorgan (South East of Caspian Sea). Journal of Applied Sciences, 8 (2). pp. 391-393. ISSN 18125654 (ISSN)

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In this study, the prevalence of HTLV-1 infection among the thalassemic patients was investigated. 181 thalassemiC patients whom referred to Talghani hospital during, Oct. 2004-Sep. 2005 were participated in this study. HTLV antibody was determined using ELISA technique. In this procedure (Diapron laboratory kit) HTLV, positive samples tested by HTLV-1 western blot (kit 2.4) to confirm, ELISA positive samples and also to detect the HTLV types, From 181 thalassemic patients, 93 (51.4%) were males. The age rate of these ranged 1-25 years, (mean of 14.11±6.5). Of these subjects 169 patients (93.4%) were received packet cell at least one unite per month 28(14.9%) of subjects were HTLV positive, while only 4.4% of them were confirmed by western blot and also for contamination with type-1 virus infection. Contamination with this virus increased, as the patients were getting older. The findings derived from this study indicated that among the thalassemic patients in Gorgan there were cases with HTLV-1, infection that was correlated with the other part of the country. It is therefore concluded, that further comprehensive studies are required to identify infected blood donations by blood donors in Gorgan. © 2008 Asian Network for Scientific Information.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - J. Appl. Sci. [Field not mapped to EPrints] AD - Golestan University of Medical Sciences, Golestan, Iran [Field not mapped to EPrints] AD - Blood and Transfusion Organization of Zahedan, Zahedan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: ELISA, Gorgan, HTLV-1 antibody, Thallesemic patients, Western blot, Blood donation, Caspian sea, ELISA, Gorgan, Thallesemic patients, Virus infection, Western blots, Blood, Viruses, Antibodies
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 18 Apr 2015 07:22
Last Modified: 07 Apr 2018 05:23
URI: http://eprints.goums.ac.ir/id/eprint/2339

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