Golestan University of Medical Sciences Repository

Lipid peroxidation in the serum of hypothyroid patients (In Gorgan-South East of Caspian Sea)

Marjani, A. and Mansourian, A.R. and Ghaemi, E.O. and Ahmadi, A. and Khori, V. (2008) Lipid peroxidation in the serum of hypothyroid patients (In Gorgan-South East of Caspian Sea). Asian Journal of Cell Biology, 3 (1). pp. 47-50. ISSN 18140068 (ISSN)

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Abstract

This study was designed to determine if lipid peroxidation can be modified by hypothyroidism. Twenty eight subjects with hypothyroidism and 33 euthyroid subjects participated in this study (2007). Blood samples were collected and serum malondialdehyde, T3, T4 and TSH were measured. An increase in lipid peroxidation (expressed as Malondialdehyde, MDA) and TSH levels and also a decrease in T4 level were observed in the hypothyroid patients when compared with control groups (p<0.001). The level of T3 was not changed when compared with control groups. The results shows that hypothyroidism may not modulate the free-radical-induced oxidative damage and that hypothyroidism may not present some protection against lipid peroxidation. Thus, the enhancedlipid peroxidation may play a role in the free-radical-induced oxidative damage of some tissues in hypothyroidism. These may show that there is an important relation between hypothyroidism and lipid peroxidation. © 2008 Academic Journals Inc.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Asian J. Cell Biol. [Field not mapped to EPrints] AD - Department of Biochemistry and Biophysics, Faculty of Medicine, Golestan University of Medical Sciences, Iran [Field not mapped to EPrints] AD - Department of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Iran [Field not mapped to EPrints] AD - Department of Laboratory Sciences, Faculty of Para-Medical, Golestan University of Medical Sciences, Iran [Field not mapped to EPrints] AD - Department of Pharmacology, Faculty of Medicine, Golestan University of Medical Sciences, Iran [Field not mapped to EPrints] AD - Department of Biochemistry and Biophysics, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Hypothyroid patients-lipid peroxidation
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 15 Apr 2015 09:12
Last Modified: 25 Feb 2017 07:41
URI: http://eprints.goums.ac.ir/id/eprint/2318

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