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Working memory learning method and astrocytes number in different subfields of rat's Hippocampus

Mehrdad, J. and Yousef, S. and Ahmad, H. and Naser, N. and Abbas, P. (2008) Working memory learning method and astrocytes number in different subfields of rat's Hippocampus. American Journal of Animal and Veterinary Sciences, 3 (1). pp. 28-31. ISSN 15574555 (ISSN)

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Abstract

The aim of this study was evaluation of the astrocytes number in different subfields of rat's Hippocampus after spatial learning with usage of Morris Water Maze technique and working memory method. In this study, between 2005-2006 years in Pasteur institute of Iran-Tehran and histological department of Gorgan University with usage of Morris Water Maze and working memory technique, we used 14 male albino wistar rats. Seventh rats were in control group and 7 rats in working memory group. After histological preparation, the slides were stained with PTAH staining for showing the Astrocytes. Present results showed significant difference in astrocytes number in CA1, CA2 and CA3 areas of hippocampus between control and reference memory group. The number of astrocytes is increased in working memory group. Then we divided the hippocampus to three parts: Anterior, middle and posterior and with compare of different area (CA1, CA2 and CA3) of hippocampus, we found that the differences between Anterior-middle and Middle-Posterior of CA1 and CA2 area of hippocampus were significant, whereas the difference between Anterior-Posterior parts was not significant in CA1 and CA2 areas. In CA3 area, the difference between Anterior-Middle and Anterior-Posterior parts was significant, whereas the difference between middle and posterior parts was not significant. We concluded that the number of astrocytes increased due to spatial learning and working memory technique. © 2008 Science Publications.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Am. J. Anim. Vet. Sci. [Field not mapped to EPrints] AD - Department of Anatomy, Gorgan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Cellular and Molecular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran [Field not mapped to EPrints] AD - Department of Physiology, Institute of Pasteur, Tehran, Iran [Field not mapped to EPrints] AD - Department of Anatomy, Gorgan University of Medical Sciences, P.O. Box 49175, 553, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Astrocytes, Hippocampus, Spatial learning, Working memory, Rattus, Rattus norvegicus
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 15 Apr 2015 08:48
Last Modified: 26 Feb 2017 10:01
URI: http://eprints.goums.ac.ir/id/eprint/2317

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