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Serum copper concentration in newborns with neural tube defects in northern Iran; A case control study

Golalipour, M.-J. and Mansourian, A.-R. and Keshtkar, A.-A. (2009) Serum copper concentration in newborns with neural tube defects in northern Iran; A case control study. Iranian Journal of Pediatrics, 19 (2). pp. 130-134. ISSN 10184406 (ISSN)

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Abstract

Objective: This study was conducted to determine the eventual association between copper deficiency in newborns with neural tube defects (NTD) in Northern Iran. A high prevalence of neural tube defects has been reported from this region. Methods: This hospital based case control study was carried out on 13 newborns having neural tube defects and 35 healthy controls in Northern Iran during 2005-2006. Serum copper was measured by spectrophotometery. Findings: Serum copper level in newborns with NTD and healthy normal newborns was 16.5 (±7.2) μmol/l and 16.7 (±6.6) μmol/ l, respectively. In case group 38.5% of newborns and in control group 28.6% had copper deficiency. Logistic regression analysis showed no association between the presence of NTD and copper deficiency (OR:1.6, 95% CI=0.3-7.1, P=0.5). Conclusion: This study showed no association between NTD and copper deficiency in newborns. © 2009 by Center of Excellence for Pediatrics, Children's Medical Center, Tehran University of Medical Sciences, All rights reserved.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Iran. J. Pediatr. [Field not mapped to EPrints] AD - Department of Embryology, Gorgan Congenital Malformations Research Center, Gorgan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Biochemistry and Biochemistry, Metabolic Research Center, Gorgan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Community Medicine, Gorgan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Anencephaly, Copper, Neural tube defects, Newborns, Spina bifida, copper, article, blood analysis, case control study, clinical article, controlled study, copper blood level, copper deficiency, disease association, human, Iran, logistic regression analysis, neural tube defect, newborn, prevalence, spectrophotometry
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 18 Apr 2015 06:45
Last Modified: 04 Mar 2017 09:56
URI: http://eprints.goums.ac.ir/id/eprint/2271

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