Golestan University of Medical Sciences Repository

Frequency of beta thalassemia trait and carrier in Gorgan, Iran

Mirbehbahani, N. and Jahazi, A. and Rabie, M.R. and Vafai, F. (2010) Frequency of beta thalassemia trait and carrier in Gorgan, Iran. Pakistan Journal of Medical Sciences, 26 (1). pp. 40-42. ISSN 1682024X (ISSN)

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Abstract

Objectives: To determine the frequency of beta-Thalassemia trait and carrier in Gorgan, Iran. Methodology: In this analytic cross sectional study conducted from March 20, 2003 until March 20, 2004, two thousands six hundred prospective grooms and brides referred to the health center of Gorgan city were studied. Globular criteria included mean corpuscular hemoglobin (MCH) and mean corpuscular volume (MCV) were determined. Hemoglobin A 2 (Hb A 2) was measured by column chromatography method. Results: The range of MCH was 13.8-35.5 pg. %15.9 of men and %27.6 of women had MCV<80fl. The frequency of beta-thalassemia trait was 9.8%. The range of HbA2 was 1.2-12% with the mean 3.06±1.5%. The frequency of beta-Thalassemia carrier (minor) was 21.4 %. Conclusion: This high frequency of beta-Thalassemia trait and carrier in Gorgan constitutes a real health problem and it necessitates more diligent effort in health care specially education and counseling. Further studies should examine the value of counseling and the prevalence of beta-Thalassemia in the children of those married.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Pak. J. Med. Sci. [Field not mapped to EPrints] AD - Golestan University of Medical Sciences, Gorgan, Golestan, Iran [Field not mapped to EPrints] AD - Islamic Azad University Gorgan Branch, Midwifery Department, Gorgan, Golestan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Beta-Thalassemia carrier, Beta-Thalassemia trait, Frequency, hemoglobin A2, adolescent, adult, article, beta thalassemia, child, column chromatography, disease carrier, female, genetic trait, health center, heterozygote, human, Iran, male, mean corpuscular volume, school child
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 20 Apr 2015 08:41
Last Modified: 20 Jun 2015 06:24
URI: http://eprints.goums.ac.ir/id/eprint/2233

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