Golestan University of Medical Sciences Repository

Evaluation of bone mineral density in premature ovarian failure

Asli, I.N. and Fallahian, M. and Seddigh, H.R. and Javadi, H. and Baharfar, N. and Assadi, M. (2010) Evaluation of bone mineral density in premature ovarian failure. Hellenic Journal of Nuclear Medicine, 13 (3). pp. 161-163. ISSN 11081430 (ISSN)

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Abstract

This study was performed to evaluate whether or not early menopause and premature ovarian failure can cause an increased risk of osteoporosis. The bone mineral density (BMD) of the 2nd and 4th lumbar spine as well as femoral neck in 29 cases with secondary amenorrhea were compared with a reference data using a dual-energy X-ray absorptiometry on a bone densitometer: Serum levels of luteinizing hormone, follicular stimulating hormone, calcium and phosphorus were also measured. Both in 20-29 years and in 30-39 years, BMD were significantly lower than their normal range as compared with a reference data from a large study of the same population (P value<0.05). At lumbar vertebrae, 2 cases had osteopenia and 17 had osteoporosis while at the femoral neck, 17 cases had osteopenia and 4 osteoporosis. Only serum levels of phosphorus had positive relationship with femoral neck BMD (P value<0.05). It may be possible to decrease fracture incidence through the early diagnosis of individuals at risk by BMD. In conclusion, our study indicates that females with early onset of menopause and premature ovarian failure had lower value of BMD in both femoral neck and lumbar vertebrae implying the need for more bone health measures.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Hell. J. Nucl. Med. [Field not mapped to EPrints] AD - Department of Nuclear Medicine, Tehran, Iran [Field not mapped to EPrints] AD - Department of Obstetrics and Gynecology, Taleghani Hospital, Shaheed Beheshti University of Medical Sciences, Tehran, Iran [Field not mapped to EPrints] AD - Department of Nuclear Medicine, 5th Azar Hospital, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Bushehr Research Center for Nuclear Medicine, Persian Gulf Biomedical Sciences Institute, Bushehr University of Medical Sciences, Bushehr, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Body mass index (BMI), Bone mineral density (BMD), Osteopenia, Osteoporosis, Premature ovarian failure, calcium, follitropin, luteinizing hormone, phosphorus, adult, article, bone densitometry, bone density, dual energy X ray absorptiometry, early menopause, female, femur neck, fracture, human, lumbar spine, lumbar vertebra, major clinical study, osteopenia, osteoporosis, premature ovarian failure, prospective study, secondary amenorrhea
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 18 Apr 2015 04:40
Last Modified: 23 May 2015 08:45
URI: http://eprints.goums.ac.ir/id/eprint/2193

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