Golestan University of Medical Sciences Repository

Vitamin deficiency in golestan province, northern Iran: A high-risk area for esophageal cancer

Malekshah, A.F. and Kimiagar, M. and Pourshams, A. and Yazdani, J. and Majd, S.K. and Goglani, G. and Jaafari, E. and Semnani, S. and Malekzadeh, R. (2010) Vitamin deficiency in golestan province, northern Iran: A high-risk area for esophageal cancer. Archives of Iranian Medicine, 13 (5). pp. 391-394. ISSN 10292977 (ISSN)

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Abstract

Objectives: Dietary factors seem to play a major role in esophageal carcinogenesis in Golestan Province, a high-incidence area for esophageal cancer in northern Iran. The current study was conducted to evaluate previous reports on severe deficiency of vitamin intake in Golestan. Methods: Using a food frequency questionnaire, food intake data were collected from 30,463 healthy participants in the Golestan Cohort Study. Intake of selected nutrients was compared with recommended daily allowance and lowest threshold intake values. Results: Vitamin A intake in the majority of participants was lower than recommended values. The proportion of participants with intakes lower than lowest threshold intake was as follows: urban men, 20%; urban women, 31%; rural men, 48%; and rural women, 64%. The pattern of vitamin C deficiency was similar to that of vitamin A, however, vitamin C deficiency was less common. Daily intake of vitamin C lower than the LTI was as follows: urban men, 6%; urban women, 9%; rural men, 13%; and rural women, 19%. On the other hand, protein intake in the majority of the general population in Golestan was higher than recommended values. Conclusion: Severe deficiency in vitamin intake among women and rural dwellers may partly explain the high incidence of EC among inhabitants in rural areas and the male:female ratio that is approximately 1 in Golestan; while EC is much more common in men in many low-incidence areas.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Arch. Iran. Med. [Field not mapped to EPrints] C2 - 20804305 [Field not mapped to EPrints] AD - Digestive Disease Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran [Field not mapped to EPrints] AD - Departments of Statistics and Biostatistics, Mazandaran University of Medical Sciences, Sari, Iran [Field not mapped to EPrints] AD - National Nutrition and Food Science, Research Institute of Shaheed Beheshti, University of Medical Sciences, Tehran, Iran [Field not mapped to EPrints] AD - Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Caspian Littoral, Esophageal cancer, Golestan, Iran, Turkmen, Vitamins, retinol, adult, article, cancer incidence, cohort analysis, controlled study, esophagus cancer, female, food frequency questionnaire, food intake, high risk population, human, Iran, major clinical study, male, nutrient uptake, protein intake, sex ratio, urban rural difference, vitamin deficiency, vitamin intake, Adult, Ascorbic Acid Deficiency, Cohort Studies, Diet, Diet Surveys, Esophageal Neoplasms, Female, Food, Humans, Iran, Male, Middle Aged, Nutrition Surveys, Nutritional Status, Risk Factors, Rural Population, Urban Population, Vitamin A Deficiency
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 15 Apr 2015 09:02
Last Modified: 20 Jun 2015 05:10
URI: http://eprints.goums.ac.ir/id/eprint/2190

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