Golestan University of Medical Sciences Repository

Thyroid function tests during first-trimester of pregnancy: A review of literature

Mansourian, A.R. (2010) Thyroid function tests during first-trimester of pregnancy: A review of literature. Pakistan Journal of Biological Sciences, 13 (14). pp. 664-673. ISSN 10288880 (ISSN)

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This literature review was conducted to summarize the main points of maternal thyroid function tests, with particular attention in the first trimester of pregnancy which accompanied with significant biochemical and metabolic alteration. The evaluation of thyroid function of either hyperthyroidism and hypothyroidism should be assessed by determination of serum Thyroid Stimulating Hormone (TSH), Thyroxine (T4), Triiodothyronine (T3), Iodine and Thyroid Autoantibodies. Glomerular filtration rate is increased during pregnancy; therefore iodine deficiency should be evaluated during the pregnancy to prevent hypothyroidism. The role which can be played by Human Chronic Gonadotropin (hCG) on stimulating the thyroid gland to become over-active was investigated. Serum level of thyroglobulin (Tg) and Thyroxin Binding Globulin (TBG) should be assessed for proper assessments of thyroid gland during pregnancy. Thyroid function tests during first-trimester of pregnancy and particularly the reference interval for thyroid function tests for pregnant women in each region has to be established, to prevent mis-diagnosis and irreversible mental and physical adverse affect for growing fetus. © 2010 Asian Network for Scientific Information.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Pak. J. Biol. Sci. [Field not mapped to EPrints] C2 - 21848058 [Field not mapped to EPrints] AD - Biochemistry and Metabolic Disorder Research Center, Gorgan Medical School, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Hyperthyroid, Hypothyroid, Pregnancy, Thyroid antibodies, Thyroxin, antibody, chorionic gonadotropin, thyroglobulin, thyroxine, thyroxine binding globulin, article, chemistry, female, first trimester pregnancy, glomerulus filtration rate, human, hyperthyroidism, hypothyroidism, immunology, methodology, pregnancy, pregnancy complication, thyroid function test, thyroid gland, Antibodies, Chorionic Gonadotropin, Female, Glomerular Filtration Rate, Humans, Hyperthyroidism, Hypothyroidism, Pregnancy, Pregnancy Complications, Pregnancy Trimester, First, Thyroglobulin, Thyroid Function Tests, Thyroid Gland, Thyroxine, Thyroxine-Binding Globulin
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 20 Apr 2015 04:46
Last Modified: 20 Jun 2015 07:25
URI: http://eprints.goums.ac.ir/id/eprint/2174

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