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The prevalence of the elevation serum alanine amino transaminase at gorgan in Northern Iran

Mansourian, A.R. and Saifi, A. and Veghari, G.R. (2011) The prevalence of the elevation serum alanine amino transaminase at gorgan in Northern Iran. Journal of Clinical and Diagnostic Research, 5 (2). pp. 246-248. ISSN 0973709X (ISSN)

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Abstract

The elevation of serum alanine aminotranferase levels is associated most commonly with some forms of liver diseases. The aim of this study was to determine the prevalence of elevated serum alanine aminotransferase levels and the possible liver damages in this region. This was a clinical laboratory based study. The data was obtained from the Danesh Medical Diagnostic Laboratory at Gorgan in northern Iran. The aminotransferase activity was measured by the pyridoxal -5-phsphate reaction. Values over 31 and 41 U/L were considered as indicative of elevated enzyme activity in females and males respectively. The findings of this study indicated that 16% of our population in general and of those who were aged 18-40 years in particular, had a form of liver disorder due to elevated enzyme, with a higher incidence among the female subjects, which seemed to be slightly higher than that reported by other studies earlier. The incidence was slightly higher among females. It seemed that high proportions of people (16%) in this region had an elevated serum enzyme activity of alanine amino-tranferase and according to well-documented reports, it might probably be associated with non-alcoholic fatty liver disease. A comprehensive study is recommended to elaborate carefully the state of liver diseases in this region of Iran.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - J. Clin. Diagn. Res. [Field not mapped to EPrints] AD - Biochemistry and metabolic Disorder research, Golestan university of medical sciences, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Alanine aminotranferase, Iran, Liver disease, alanine aminotransferase, pyridoxal 5 phosphate, adult, aged, alanine aminotransferase blood level, article, clinical laboratory, controlled study, enzyme activity, enzyme analysis, enzyme induction, female, human, incidence, Iran, liver injury, male, nonalcoholic fatty liver, population risk, sex difference, sex ratio
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 18 Apr 2015 08:03
Last Modified: 16 May 2015 08:58
URI: http://eprints.goums.ac.ir/id/eprint/2126

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