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A review on the metabolic disorders of iodine deficiency

Mansourian, A.R. (2011) A review on the metabolic disorders of iodine deficiency. Pakistan Journal of Biological Sciences, 14 (7). pp. 412-424. ISSN 10288880 (ISSN)

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Abstract

Iodine is in the crucial parts of two hormones of T4 and T3 produced by the thyroid glands which are essential for all the aspects of human metabolisms. It is demonstrated that iodine deficiency can be considered as sole cause of many thyroid abnormalities including mental disorders. Iodine deficiency of sufficient degree to cause hypothyroidism during fetus life and early infancy will be accompanied with brain abnormality possibly to the stage of mental retardation. The iodine deficiency among subjects in their early stage of childhood is not as severe as those in their fetus or infancy. In adult subjects the sever iodine deficiency can be also associated with mental disorders due to the direct side effects of hypothyroidism occurred by lack of iodine. The clinical manifestation of iodine deficiency show itself with psychological disorders in adult subjects. The status of iodine within blood can be evaluated through measurement of urinary iodine level and the low urinary concentration is an indicative of hypothyroidism. Mental retardation and brain damage due to iodine deficiency can be prevented if iodine supplementation prescribed duly on time. © 2011 Asian Network for Scientific Information.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Pak. J. Biol. Sci. [Field not mapped to EPrints] C2 - 21902053 [Field not mapped to EPrints] AD - Biochemistry and Metabolic Disorder Research Center, Gorgan Medical School, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Adult, Brain damage, Hypothyroidism, Infant, Mental retardation, iodine, adult, brain, female, human, hypothyroidism, malnutrition, mental deficiency, metabolic encephalopathy, metabolism, newborn, pregnancy, prenatal development, review, urine, Adult, Brain, Brain Diseases, Metabolic, Female, Humans, Hypothyroidism, Infant, Newborn, Iodine, Malnutrition, Mental Retardation, Pregnancy
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 20 Apr 2015 05:48
Last Modified: 17 Jan 2017 10:51
URI: http://eprints.goums.ac.ir/id/eprint/2112

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