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Antibiotic prophylaxis during extracorporeal shock wave lithotripsy in the prevention of urinary tract infections in patients with sterile urine before the procedure

Ghazimoghaddam, B. and Tajari, H. and Gholipoor, M. and Balmehd, M. (2011) Antibiotic prophylaxis during extracorporeal shock wave lithotripsy in the prevention of urinary tract infections in patients with sterile urine before the procedure. Journal of Clinical and Diagnostic Research, 5 (4). pp. 772-774. ISSN 0973709X (ISSN)

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Abstract

Introduction: There are controversies in the literature regarding the need and the duration of antibiotic prophylaxis in patients with extracorporeal shock wave lithotripsy (ESWL), who had a negative urine culture before the operation. This study was performed to evaluate the efficacy of the antibiotic prophylaxis in patients with proven sterile urine before they underwent ESWL. Materials and Methods: In this clinical trial, 150 patients with renal or urethral stones and sterile urine were examined for bacteriuria (positive urine culture) following ESWL. These patients were classified into 3 groups which received either a single dose of oral co-trimoxazole (Tab, 400/80 mg)- group A, a single dose of nitrofurantoin (Tab:100mg) -group B and no treatment- group C. Patients were followed with urine analysis and urine culture after two weeks. Results: The occurrence of post-ESWL urinary infections (positive urine culture) was 14% in group A, 10% in group B and 14% in group C. The complications among the groups were not statistically significant. Conclusion: The incidence of urinary tract infections after ESWL is extremely low, provided that in patients who had sterile urine before ESWL, prophylaxis antibiotics do not seem to be necessary.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - J. Clin. Diagn. Res. [Field not mapped to EPrints] AD - Golestan University of Medical Sciences, Urology department, 5 Azar Hospital, 5 Azar boulevard, Gorgan, Golestan province, Iran [Field not mapped to EPrints] AD - Dept. of Urology, Golestan University of Medical Sciences, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Antibiotic, ESWL, Nephrolithiasis, Prophylaxis, UTI, cotrimoxazole, nitrofurantoin, adult, antibiotic prophylaxis, article, bacteriuria, controlled clinical trial, controlled study, dose response, drug efficacy, extracorporeal lithotripsy, female, human, major clinical study, male, nephrolithiasis, single drug dose, urethra stone, urinalysis, urinary tract infection, urine culture
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 18 Apr 2015 08:37
Last Modified: 14 May 2015 03:56
URI: http://eprints.goums.ac.ir/id/eprint/2104

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