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The role of gated myocardial perfusion scintigraphy (GMPS) in myocarditis: A case report and review of the literature

Javadi, H. and Jallalat, S. and Pourbehi, G. and Semnani, S. and Mogharrabi, M. and Nabipour, I. and Ravanbod, M. and Amini, A. and Assadi, M. (2011) The role of gated myocardial perfusion scintigraphy (GMPS) in myocarditis: A case report and review of the literature. Nuclear Medicine Review, 14 (2). pp. 112-115. ISSN 15069680 (ISSN)

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Acute myocarditis is one of the most challenging diagnoses and treatments in cardiology. The acute viral myocarditis diagnosis is usually based on high suspicion, history taking, and physical examination. Likewise, the use of chest radiography, electrocardiography (ECG), and echocardiography is helpful in making a final diagnosis, but all are non-specific. In addition, in imaging query, magnetic resonance imaging (MRI) depicts some degree of cardiac inflammation in the course of myocarditis. Myocardial perfusion imaging (MPI) has also been shown to be useful in diagnosis, and this noninvasive technique diminishes the need for myocardial biopsy. The current study presents the diagnostic and prognostic role of MPI in a 25-year-old patient with suspected myocarditis. The patient underwent gated-technetium-99m-lablled, methoxyisobutyl isonitrile, single photon emission computed tomography (Gated 99mTc-MIBI SPECT) that showed nonheterogeneous absorption with remarkable decreased radiotracer uptake in the myocardium in both stress and rest phases. In addition, the gated mode demonstrated decreased wall motion and thickening of the myocardium with a sum motion score (SMS) of 28, a sum thickening score (STS) of 15, and a measured LVEF of 34%. The study concludes that 99mTC-MIBI SPECT imaging is a useful modality in the preparation of supplementary diagnostic and prognostic information in viral myocarditis. Copyright © 2011 Via Medica.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Nucl. Med. Rev. [Field not mapped to EPrints] C2 - 22219153 [Field not mapped to EPrints] AD - Golestan Research Centre of Gastroenterology and Hepatology (GRCGH), Golestan University of Medical Sciences (GUOMS), Gorgan, Iran [Field not mapped to EPrints] AD - Persian Gulf Nuclear Medicine Research Centre, Bushehr University of Medical Sciences, Bushehr 3631, Iran [Field not mapped to EPrints] AD - Persian Gulf Marine Medicine Biotechnology Research Center, Bushehr University of Medical Sciences, Bushehr, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Echocardiography, Electrocardiography (ECG), Gated myocardial perfusion scintigraphy (GMPS), Myocarditis, methoxy isobutyl isonitrile technetium tc 99m, adult, article, case report, diagnostic value, echocardiography, electrocardiogram, heart scintiscanning, human, male, medical history, nuclear magnetic resonance imaging, physical examination, prognosis, single photon emission computer tomography, thorax radiography, virus myocarditis, Adult, Cardiac-Gated Single-Photon Emission Computer-Assisted Tomography, Humans, Male, Myocardial Perfusion Imaging, Myocarditis, Prognosis, Radiopharmaceuticals, Stroke Volume, Technetium Tc 99m Sestamibi, Ventricular Function, Left
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 19 Apr 2015 06:55
Last Modified: 14 May 2015 05:09
URI: http://eprints.goums.ac.ir/id/eprint/2080

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