Golestan University of Medical Sciences Repository

High resolution imaging of IgG and IgM molecules by scanning tunneling microscopy in air condition

Saber, R. and Sarkar, S. and Gill, P. and Nazari, B. and Faridani, F. (2011) High resolution imaging of IgG and IgM molecules by scanning tunneling microscopy in air condition. Scientia Iranica, 18 (6). pp. 1643-1646. ISSN 10263098 (ISSN)

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Abstract

A scanning tunneling microscope is a powerful tool for obtaining micrographs from conductive and semiconductive materials. The imaging technique has recently been improved for microscopy of nanostructured biomaterials on highly ordered atomic surfaces. We describe, here, high resolution imaging of individual IgM and IgG using a scanning tunneling microscope (Nama-STM) in air condition. The biomolecules were immobilized on the surface of Highly Ordered Pyrolytic Graphite (HOPG). Obtained micrographs could reveal structural details of immunoglobulins G and M on the atomically flat surfaces. Obtained results confirmed that STM could be more useful than other microscopy techniques for the analysis of single biomolecules. © 2012 Sharif University of Technology. Production and hosting by Elsevier B.V. All rights reserved.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Sci. Iran. [Field not mapped to EPrints] AD - Nanotechnology Group, Research Center for Science and Technology in Medicine (RCSTIM), Tehran University of Medical Sciences (TUMS), P.O. Box 1978647653, Tehran, Iran [Field not mapped to EPrints] AD - Department of Medical Nanotechnology (Nanomedicine), Faculty of Advanced Medical Technologies, Golestan University of Medical Sciences (GOUMS), P.O. Box 1673978964, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Electrical and Computer Engineering, Isfahan University of Technology, P.O. Box 84156833111, Isfahan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Air condition, IgG, IgM, Nanostructured biomaterials, STM, Air conditions, IgG, IgM, Nanostructured biomaterials, STM, Biological materials, Biomolecules, Conductive materials, Imaging techniques, Microscopes, Pyrolysis, Surfaces, Scanning tunneling microscopy, air conditioning, antibody, microscopy, nanotechnology, scanning tunnelling microscopy
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 20 Apr 2015 08:01
Last Modified: 16 May 2015 15:14
URI: http://eprints.goums.ac.ir/id/eprint/2074

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