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Serum level of lactate dehydrogenase, homocystein, hemoglobin and platelet in preeclampsia

Nosrat, B.S. and Azarhoosh, R. and Borghei, A. and Sedaghati, M. and Besharat, S. and Ghaemi, E. (2011) Serum level of lactate dehydrogenase, homocystein, hemoglobin and platelet in preeclampsia. Pakistan Journal of Medical Sciences, 27 (5). pp. 1014-1017. ISSN 1682024X (ISSN)

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Objectives: Pre-eclampsia affects approximately 5-8% of pregnant women. The aim of this study was to compare the serum level of Lactate dehydrogenase (LDH), Homocystein, Hemoglubin and platelet in pregnant women diagnosed as pre-eclampsia and a normal group in Gorgan city, Northeastern Iran from 2007-2008. Methodology: In this case control study, 50 cases of pre-eclampsia were compared with the control group women hospitalized in Dezyani hospital. Pre-eclampsia criteria were: Blood pressure more than or equal to 140/90 mm hg and Proteinuria greater or equal to 300 mg/ 24 hours urine sample in the third trimester. Hemoglobin, platelet, LDH and hemocystein were measured. Data were analyzed by the mean of SPSS-14 program & Chi-2 or t-student were used. Results: The difference of BMI and family incomes was significant between two groups (P-value<0.01). LDH level was not statistically different between healthy and pre-eclamptic individuals. Six cases (12%) in controls and 9 cases (18%) in pre-eclamptic group had thrombocytopenia (P-value>0.01). Hemocystein level was more than normal range in five patients with pre-eclampsia (P-value<0.001). Conclusions: In this study, hemocystein level was significantly higher in pre-eclampsia patients but LDH, hemoglobin and platelet level had no significant difference.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Pak. J. Med. Sci. [Field not mapped to EPrints] AD - Specialist in Social Medicine, Golestan University of Medical Sciences, Iran [Field not mapped to EPrints] AD - Gynecologist, Golestan University of Medical Sciences, Infectious Disease Research Center, Iran [Field not mapped to EPrints] AD - Pathologist, Golestan University of Medical Sciences, Golestan Research Center of Gastroenterology and Hepatology, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Eclampsia, Hemocystein, Hemoglobin, Lactate dehydrogenase (LDH), Platelet, Preeclampsia, Proteinuria, hemoglobin, homocysteine, lactate dehydrogenase, adult, amino acid blood level, article, blood pressure measurement, body mass, case control study, clinical article, comparative study, controlled study, female, hemoglobin blood level, human, income, Iran, lactate dehydrogenase blood level, normal value, preeclampsia, pregnant woman, proteinuria, third trimester pregnancy, thrombocyte count, thrombocytopenia
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 20 Apr 2015 04:27
Last Modified: 16 May 2015 10:56
URI: http://eprints.goums.ac.ir/id/eprint/2064

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