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Immunomodulatory properties of mesenchymal stem cells: Cytokines and factors

Soleymaninejadian, E. and Pramanik, K. and Samadian, E. (2012) Immunomodulatory properties of mesenchymal stem cells: Cytokines and factors. American Journal of Reproductive Immunology, 67 (1). pp. 1-8. ISSN 10467408 (ISSN)

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Abstract

Mesenchymal stem cells (MSCs) are defined as undifferentiated cells that are capable of self renewal and differentiation into several cell types such as chondrocyte, adipocyte, osteocyte, myocyte, hepatocyte, and neuron-like cells. MSC can be isolated from bone marrow, umbilical cord blood, adipose tissue, placenta, periosteum, trabecular bone, synovium, skeletal muscle, and deciduous teeth. Immunomodulatory of MSCs is one of the important issues nowadays, because this aspect can be clinically applied for graft-versus-host and autoimmune diseases. In this review, we tried to discuss in detail about cytokines and factors such as members of the transforming growth factor superfamily (transforming growth factor-β), hepatic growth factors (HGF), prostaglandin E2 (PGE2), IL-10, indolamine 2,3-dioxygenase (IDO), nitric oxide (NO), heme oxygenase-1 (HO-1), and human leukocyte antigen-G (HLA-G) that are involved in immunomodulatory of MSCs. © 2011 John Wiley & Sons A/S.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Am. J. Reprod. Immunol. [Field not mapped to EPrints] C2 - 21951555 [Field not mapped to EPrints] AD - Center for Biotechnology, Institute of Science and Technology, Jawaharlal Nehru Technological University, Hyderabad, India [Field not mapped to EPrints] AD - NIT, Biotechnology and Medical Engg, Rourkela, India [Field not mapped to EPrints] AD - Department of Molecular medicine, Golestan University of Medical Sciences, School of New Medical Technologies, Golestan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Cytokines, Factors, Immunomodulation, Mesenchymal stem cells, 15 hydroxyprostaglandin dehydrogenase, cytokine, gamma interferon, glial cell line derived neurotrophic factor, growth differentiation factor 15, heme oxygenase 1, HLA G antigen, immunoglobulin E, indoleamine 2,3 dioxygenase, interleukin 10, interleukin 12, interleukin 2, interleukin 4, interleukin 5, lysosome associated membrane protein 1, natural killer cell receptor NKG2D, nitric oxide, prostaglandin E receptor, prostaglandin E synthase, prostaglandin E2, prostaglandin synthase, protein p53, scatter factor, transforming growth factor beta, tumor necrosis factor alpha, apoptosis, article, B lymphocyte, bone marrow cell, cancer cell, carcinogenesis, catabolism, cell differentiation, cell growth, cell invasion, cellular immunity, cytokine production, cytokine release, cytolysis, down regulation, fatty acid metabolism, fetus growth, fibromyalgia, gene inactivation, growth inhibition, human, immunoglobulin production, immunomodulation, inflammation, intracellular signaling, lymphocyte, lymphocyte proliferation, lymphoid cell, macrophage, major histocompatibility complex, mesenchymal stem cell, monocyte, natural killer cell, nonhuman, pregnancy, priority journal, protein expression, regulatory T lymphocyte, Th2 cell, trophoblast, Adipose Tissue, Bone Marrow Cells, Cell Differentiation, Cell Proliferation, Dinoprostone, Fetal Blood, Graft vs Host Disease, Heme Oxygenase-1, Hepatocyte Growth Factor, HLA-G Antigens, Humans, Immunity, Innate, Immunomodulation, Indoleamine-Pyrrole 2,3,-Dioxygenase, Interleukin-10, Mesenchymal Stem Cell Transplantation, Mesenchymal Stem Cells, T-Lymphocytes, Transforming Growth Factor beta
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 15 Apr 2015 08:51
Last Modified: 13 May 2015 05:58
URI: http://eprints.goums.ac.ir/id/eprint/2058

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