Golestan University of Medical Sciences Repository

A novel hydrogen peroxide biosensor based on modified electrode with hemoglobin and zinc oxide nanoparticles

Negahdary, M. and Noughabi, M.T. and Rezaei, E. and Mazdapour, M. and Farasat, A. and Arabnezhad-Khanooki, T. and Yousefi-Telori, B. and Mirzaeinasab, F. (2012) A novel hydrogen peroxide biosensor based on modified electrode with hemoglobin and zinc oxide nanoparticles. Advances in Environmental Biology, 6 (3). pp. 1095-1103. ISSN 19950756 (ISSN)

[img]
Preview
PDF - Published Version
Download (360kB) | Preview

Abstract

In this study, direct electron transfer between immobilized hemoglobin (Hb) and zinc oxide nanoparticles modified carbon paste electrode was studied. Direct electrochemical response of Hb on the modified electrode can be achieved and a couple of well-defined and nearly reversible cyclic voltammetric peaks of Hb can be observed in a phosphate solution. The Hb immobilized on the Modified electrode with Zno Nps displayed a pair of redox peaks in 0.1 M pH 7.0 PBS with a formal potential of + (292 ± 2) mV (vs. SCE). Hb adsorbed on the modified electrode surface shows a good activity for the reduction of hydrogen peroxide (H2O2). The reduction peak currents were proportional linearly to the concentration of hydrogen peroxide. The Hb/ Zno Nps/ CPE had good repeatability and stability for the determination of H2O2.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Adv. Environ. Biol. [Field not mapped to EPrints] AD - Young Researchers Club, Marvdasht Branch, Islamic Azad University, Marvdasht, Iran [Field not mapped to EPrints] AD - Department of Basic Science, Gonabad University of Medical Sciences, Gonabad, Iran [Field not mapped to EPrints] AD - Shiraz University of medical sciences, Shiraz, Iran [Field not mapped to EPrints] AD - Department of Biology, Islamic Azad University of pharmaceutical science, Tehran, Iran [Field not mapped to EPrints] AD - Biology Group, Basic Science Faculty, IHU University, Tehran, Iran [Field not mapped to EPrints] AD - Department of Biology, Payam-e-Noor University, Isfahan, Iran [Field not mapped to EPrints] AD - Faculty of Advanced Medical Technology, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Biology, Payam-e-Noor University, Taft, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Biosensor, Hemoglobin, Hydrogen peroxide, Zinc oxide nanoparticles
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 15 Apr 2015 08:47
Last Modified: 12 May 2015 09:49
URI: http://eprints.goums.ac.ir/id/eprint/2034

Actions (login required)

View Item View Item