Golestan University of Medical Sciences Repository

Lambda phage nanoparticles for targetomics

Ghaemi, A. and Tabaraei, A. and Gill, P. and Soleimanjahi, H. and Gorji, A. (2012) Lambda phage nanoparticles for targetomics. Biotechnology, 11 (2). pp. 95-99. ISSN 1682296X (ISSN)

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Abstract

The emerging aim of drug delivery requires the bioactive or therapeutic molecule to be protected from degradation and reach its target cell and intracellular location. Target specificity of nanoparticles is a prerequisite to attain the concentration of therapeutic agent required for therapeutic efficacy in the target tissue while minimising adverse effects on other parts of the body. Therefore, there is an urgent need for improvement of more effective drug delivery systems to direct the anticancer drugs to cancer cells, specifically. In the paper, we have described advantages of Lambda bacteriophage over other drug delivery vectors and proposed it as promising drug delivery vehicle. © 2012 Asian Network for Scientific Information.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Biotechnology [Field not mapped to EPrints] AD - Golestan Research Center of Gastroenterology and Hepatology-GRCGH, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Microbiology, School of Medicine, Golestan University of Medical Sciences, P.O. Box 49175-1141, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Medical Nanotechnology, Golestan University of Medical Sciences and Health Care, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Virology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran [Field not mapped to EPrints] AD - Shefa Neuroscience Research Center, Tehran, Iran [Field not mapped to EPrints] AD - Institut fur Physiologie i, Westfälische Wilhelms-Universität Münster, Robert-Koch-Strasse, Münster, Germany [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Cancer therapy, Drug delivery, Lambda bacteriophage, Phage display, Targetomics, Adverse effect, Anticancer drug, Cancer cells, Cancer therapy, Delivery vector, Drug delivery system, Drug delivery vehicles, Phage display, Target cells, Target tissues, Targetomics, Therapeutic agents, Therapeutic efficacy, Therapeutic molecules, Bacteriophages, Degradation, Nanoparticles, Tissue, Drug delivery, Enterobacteria phage lambda
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 15 Apr 2015 10:05
Last Modified: 20 Jun 2015 04:36
URI: http://eprints.goums.ac.ir/id/eprint/2012

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