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Different features in Wegener's granulomatosis: Report of five cases

Sedighi, S. and Aghaie, M. and Zahedi, M. and Mozafari, N. and Roshandel, G. (2012) Different features in Wegener's granulomatosis: Report of five cases. Journal of Clinical and Diagnostic Research, 5 (7). pp. 1437-1439. ISSN 2249782X (ISSN)

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Abstract

Wegener's granulomatosis (WG) is an autoimmune inflammatory condition. It is often a rapidly progressive and potentially fatal disease. The clinical presentation of WG can be so diverse that the list of its differential diagnosis is vast, ranging from infectious diseases to other vasculitis (e.g. Behcet's disease), as well as malignancies. The exact aetiology of WG remains unclear. The upper airway diseases including sinusitis, oral lesions and otitis media are the most common presenting features of WG. In this paper, we have described 5 WG cases. They had different presentations and chief complaints. Some of them presented with upper airways diseases, while the others mainly suffered from the manifestations of pulmonary involvement. Although all of them were finally diagnosed as WG cases, the processes of the work up for the diagnosis as well as the outcome of the disease were not the same. So, the diversities in the presentation should be mentioned in the management of the WG suspected patients.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - J. Clin. Diagn. Res. [Field not mapped to EPrints] AD - Department of Reumatology, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Department of internal medicine, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Golestan Research Center of Gastroenterology and Haepatology, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Digestive Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Case report, Manifestations, Wegener's granulomatosis, cotrimoxazole, cyclophosphamide, cyclosporin, hydrocortisone, methotrexate, methylprednisolone, myeloblastin, neutrophil cytoplasmic antibody, prednisolone, adolescent, adult, antibody detection, article, bone swelling, bronchitis, bronchus biopsy, clinical article, clinical feature, differential diagnosis, electromyography, exophthalmos, eye examination, female, gingivitis, hemoptysis, histopathology, human, human tissue, laboratory diagnosis, lung hemorrhage, lung infiltrate, lung nodule, maculopapular rash, male, nasal biopsy, otorrhea, papule, physical examination, polyneuropathy, respiratory distress, scleritis, thorax radiography, treatment outcome, Wegener granulomatosis
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 18 Apr 2015 08:21
Last Modified: 13 May 2015 05:00
URI: http://eprints.goums.ac.ir/id/eprint/2002

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