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Third-degree heart block in thalassemia major: A case report

Maleki, A.R. and Nikyar, B. and Hosseini, S.M. (2012) Third-degree heart block in thalassemia major: A case report. Iranian Journal of Pediatrics, 22 (2). pp. 260-264. ISSN 10184406 (ISSN)

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Background: First and second-degree heart blocks are partly common rhythm disorders in thalassemic patients but complete heart block is a very rare complication of iron overload cardiomyopathy. Case Presentation: This 15-year-old boy, a known case of major β-thalassemia was admitted to our emergency unit with dyspnea and cough because of decompensated heart failure. The electrocardiogram showed complete heart block with junctional escape rhythm. Interestingly, his previous electrocardiogram taken 2 months earlier, had some PVC and second degree, Mobitz type 1 (Wenckebach) heart block. After improvement of dyspnea and control of blood pressure in normal range, the patient was referred to ER. A dual-chamber permanent pacemaker was implanted and his symptoms improved, but he died 24 days after discharge from hospital. Conclusion: We present a rare case of complete heart block after a second-degree (Mobitz 1) heart block that was due to severe iron overload cardiomyopathy. © 2012 by Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Iran. J. Pediatr. [Field not mapped to EPrints] AD - Student Research Committee, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Pediatrics, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Physiology, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: β-Thalassemia, Arrhythmia, Cardiomyopathy, Iron overload, captopril, ceftriaxone, deferoxamine, digoxin, dopamine, furosemide, hemoglobin A, hemoglobin A2, hemoglobin F, spironolactone, abdominal pain, adolescent, article, backache, blood culture, blood pressure regulation, blood transfusion, bradycardia, cardiovascular system examination, case report, chelation therapy, complete heart block, coughing, disease association, disease duration, dyspnea, emergency ward, fever, heart death, heart dilatation, heart ventricle extrasystole, heart ventricle tachycardia, hemoglobin blood level, hepatomegaly, hospital admission, human, implanted heart pacemaker, jaundice, laboratory test, lethargy, lung auscultation, male, medical history, mitral valve regurgitation, oxygen saturation, patient compliance, pericardial effusion, periorbital edema, peripheral edema, physical examination, pleura effusion, respiratory distress, splenectomy, stomach distension, systolic dysfunction, tachypnea, thalassemia major, thorax radiography, transthoracic echocardiography, treatment failure, tricuspid valve regurgitation, Wenckebach period
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 18 Apr 2015 06:52
Last Modified: 12 May 2015 06:22
URI: http://eprints.goums.ac.ir/id/eprint/2001

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