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Effect of peppermint oil on serum lipid peroxidation and hepatic enzymes after immobility stress in mice

Marjani, A. and Rahmati, R. and Mansourian, A.R. and Veghary, G. (2012) Effect of peppermint oil on serum lipid peroxidation and hepatic enzymes after immobility stress in mice. Open Biochemistry Journal, 6. pp. 51-55. ISSN 1874091X (ISSN)

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Abstract

This study was undertaken to determine the influences of various doses of peppermint oil on the hepatic enzymes, alanine transaminase, apartate tranaminase, alkaline phosphotase and gamma glutamyl transferase and the level of malondialdehyde in the serum of mice with and without immobility stress. The mice exposed to drink water, 0.9, 27 and 60 mg/kg peppermint oil from the days 1 to 5 for a period of 4 h before and after immobility stress. Serum MDA increased in treatment group II, III and IV after immobility stress. There was a significant decrease in ALT in treatment group III and IV after immobility stress. There were also significant decreases in ALP and GGT in treatment group IV after immobility stress. This result may suggest that, MDA level is higher in immobilization stress group than in the un-immobilized animals in serum and this results show that enzyme activities decreased after immobilization stress. © Marjani et al.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Open Biochem J. [Field not mapped to EPrints] AD - Department of Biochemistry and Biophysics and Nutrition, Biochemistry and Metabolic Disorder Research Center, Golestan province, Gorgan, Iran [Field not mapped to EPrints] AD - Department of Physiology, Faculty of Medicine, Golestan University of Medical Sciences, Golestan province, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Hepatic enzymes, Immobility stress, Lipid peroxidation, Peppermint oil, alanine aminotransferase, alkaline phosphatase, aspartate aminotransferase, gamma glutamyltransferase, malonaldehyde, peppermint oil, alanine aminotransferase blood level, alkaline phosphatase blood level, animal experiment, article, aspartate aminotransferase blood level, controlled study, drug dose comparison, enzyme activity, gamma glutamyl transferase blood level, immobilization stress, lipid peroxidation, male, morning dosage, mouse, nonhuman, priority journal
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 19 Apr 2015 07:19
Last Modified: 12 May 2015 09:08
URI: http://eprints.goums.ac.ir/id/eprint/1987

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