Golestan University of Medical Sciences Repository

Genetic characterization of Echinococcus granulosus in camels, cattle and sheep from the south-east of Iran indicates the presence of the G3 genotype

Hajialilo, E. and Harandi, M.F. and Sharbatkhori, M. and Mirhendi, H. and Rostami, S. (2012) Genetic characterization of Echinococcus granulosus in camels, cattle and sheep from the south-east of Iran indicates the presence of the G3 genotype. Journal of Helminthology, 86 (3). pp. 263-270. ISSN 0022149X (ISSN)

[img]
Preview
PDF - Published Version
Download (1MB) | Preview

Abstract

Echinococcus granulosus, the aetiologic agent of cystic echinococcosis (CE), is one of the most important zoonotic helminthes worldwide. Isolates of the parasite show considerable genetic variation in different intermediate hosts. Several genotypes and species are described in different eco-epidemiological settings. This study investigated E. granulosus genotypes existing in livestock and humans from the province of Kerman, located in south-eastern Iran, using sequencing data of cox1 and nad1 mitochondrial genes. Fifty-eight E. granulosus isolates, including 35 from sheep, 11 from cattle, 9 from camels and 3 from goats, were collected from slaughterhouses throughout Kerman. One human isolate was obtained from a surgical case of CE. Mitochondrial cox1 and nad1 regions were amplified using polymerase chain reaction (PCR) and 38 isolates were sequenced. Genotypes G1 (73.7%), G3 (13.2%) and G6 (13.1%) were identified from the isolates. G1 was the most common genotype from sheep (86.7%), cattle (80%), camels (44.4%) and goats (100%). Sheep, cattle and camels were also found to be infected with the G3 genotype (buffalo strain). The human isolate was identified as the G6 genotype. Results showed that the G3 genotype occurred in different animal hosts in addition to G1 and G6 genotypes. © 2011 Cambridge University Press.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - J. Helminthol. [Field not mapped to EPrints] C2 - 21749740 [Field not mapped to EPrints] AD - Department of Parasitology, School of Medicine, Kerman University of Medical Sciences, Kerman 76169-14111, Iran [Field not mapped to EPrints] AD - Department of Medical Parasitology and Mycology, Infectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan 49155, Iran [Field not mapped to EPrints] AD - Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran 14155-6446, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: cyclooxygenase 1, nad1 protein, protein, unclassified drug, animal experiment, article, camel, cattle, Echinococcus granulosus, genetic analysis, genotype, human, Iran, nonhuman, nucleotide sequence, polymerase chain reaction, sheep, slaughterhouse, Animal Diseases, Animals, Camels, Cattle, Cyclooxygenase 1, DNA, Helminth, DNA, Mitochondrial, Echinococcosis, Echinococcus granulosus, Genetic Variation, Genotype, Humans, Iran, NADH Dehydrogenase, Phylogeny, Polymerase Chain Reaction, Sheep, Zoonoses, Animalia, Bos, Camelidae, Capra hircus, Echinococcus granulosus, Ovis aries, Vermes
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 19 Apr 2015 04:02
Last Modified: 11 May 2015 16:04
URI: http://eprints.goums.ac.ir/id/eprint/1975

Actions (login required)

View Item View Item