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Antimicrobial resistance patterns of urinary tract pathogens in young children from Gorgan, Northern Iran

Maleki, A.R. and Jamshir, M. and Beykmohamadi, A.R. and Eivazi, Y. and Maleki, H. (2013) Antimicrobial resistance patterns of urinary tract pathogens in young children from Gorgan, Northern Iran. Journal of Pediatric Infectious Diseases, 8 (4). pp. 161-166. ISSN 13057707 (ISSN)

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Abstract

The antibiotic resistance or susceptibility patterns of common bacterial pathogens vary between geographical regions. We investigated the antibiotic resistance pattern of common uropathogens in a population of young children. In this cross- sectional retrospective study, children suspected of having urinary tract infection (UTI) that were referred to Taleghani Pediatric Hospital from March 2009 until March 2010 were included. Urine cultures were performed before initiation of antibiotics. Demographic information and results of cultures and antibiograms were obtained from the laboratory archive. Cultures with colony count ≥ 105 cfu/ml in midstream urine samples or any colony count in the suprapubic samples were considered to be positive. Antimicrobial susceptibility testing was performed using the Kirby Bauer disc diffusion method. We evaluated 7844 urine cultures of which 153 (2%) were obtained from supra-pubic aspiration route. 3839 (48.9%) were male. In total, 533 (6.8%) of cultures were positive (64.2% were female). E. coli was the most common organism in positive samples in both sexes, but it was significantly more common in the females than males (83.3% vs. 75.4%, P < 0.05). E. coli showed the highest percentage of resistance to ampicillin (84.1%) and the lowest resistance to amikacin (11%). We found that E. coli was the predominant bacterial pathogen and that the antimicrobial resistance patterns of the different uropathogens were highly variable, emphasizing the importance of continuous surveillance of trends in resistance patterns of uropathogens. © 2013 - IOS Press and the authors. All rights reserved.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - J. Pediatr. Infect. Dis. [Field not mapped to EPrints] AD - Deputy of Research and Technology, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran [Field not mapped to EPrints] AD - Young Researchers Club, School of Medicine, Islamic Azad University, Tonekabon Branch, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: anibiotics, children, Drug resistance, urinary tract infection, amikacin, amoxicillin, ampicillin, antibiotic agent, cefixime, ceftriaxone, ciprofloxacin, cotrimoxazole, gentamicin, nalidixic acid, nitrofurantoin, oxacillin, vancomycin, antibiotic resistance, antibiotic sensitivity, antibiotic therapy, article, bacterial count, bacterium culture, bacterium identification, bacterium isolation, child, childhood disease, Citrobacter, cross-sectional study, disk diffusion, Enterobacter, Escherichia coli, female, human, infant, Iran, Klebsiella, major clinical study, male, nonhuman, priority journal, Proteus, Pseudomonas aeruginosa, retrospective study, sex difference, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus saprophyticus, suprapubic aspiration, urinalysis, urinary tract infection, urine culture, uropathogenic Escherichia coli
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 19 Apr 2015 05:01
Last Modified: 23 Jan 2017 10:22
URI: http://eprints.goums.ac.ir/id/eprint/1926

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