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The comparison of acute myocardial infarction serum anticardiolipin antibody with healthy subjects, in Gorgan (northern Iran)

Ahmadi, A.R. and Joshaghani, H.R. and Mansourian, A.R. and Salehi, A. and Behnampour, N. (2013) The comparison of acute myocardial infarction serum anticardiolipin antibody with healthy subjects, in Gorgan (northern Iran). Pakistan Journal of Biological Sciences, 16 (2). pp. 92-96. ISSN 10288880 (ISSN)

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Abstract

Arthrosclerosis considered one of the most important causes of morbidity and mortality in industrial and developing countries. The rate of myocardial infarction in some countries is about 2 million annually with 1/4 of them is leading to death. This study was a case-control research, which was carried out as cross-sectional project in two groups, healthy and case subjects. The mean age and standard deviation of patients and control groups were nearly equal (55±10). The ELISA technique was applied to measure the serum antibody level. The sample populations in each group were exactly the same (120 person in each group). The gender distribution in case and control group was 44 female, 76 male and 45 female and 75 male, respectively. The Mean±SD of IgM in case group and control groups were 3.10± 2.54 and 1.54±1.00, respectively. TheMeantSD forlgG incase and control groups were 5.90±3.84 and 3.08±1.95, respectively. The differences, between the mean of IgM and IgG in two groups of cases and control statistically were significant (p = 0.0001). In case group the Meani±SD for IgM for men and woman were 2.98±1.97 and 3.17±2.83, respectively, which this differences statistically, were not significant. In case group the Meant±SD forlg G were 5.14±3.45 and 6.35. The above findings indicated that the average of both IgG and IgM are higher among men compared to women. Due to high prevalence of acute coronary syndrome in Iran, the determination of anticardiolipin antibody (IgG) are applied for suspected acute coronary syndrome patients and further prevention measure should be taken for patient with higher serum anticardiolipin antibody. © 2013 Asian Network for Scientific Information.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Pak. J. Biol. Sci. [Field not mapped to EPrints] C2 - 24199493 [Field not mapped to EPrints] AD - Laboratory Sciences Research Center, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Metabolic Disorder Research Center, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Cardiovascular Research Center, Gorgan Medical School, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] AD - Hematology and Oncology Research Center, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Anticardiolipin antibody, Arthrosclerosis, Myocardial infarction, Northern Iran, biological marker, cardiolipin antibody, aged, article, blood, case control study, comparative study, female, heart infarction, human, Iran, male, middle aged, reference value, Aged, Antibodies, Anticardiolipin, Biological Markers, Case-Control Studies, Female, Humans, Iran, Male, Middle Aged, Myocardial Infarction, Reference Values
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 20 Apr 2015 04:57
Last Modified: 14 May 2015 19:45
URI: http://eprints.goums.ac.ir/id/eprint/1898

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