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Endoscopic screening for esophageal squamous cell carcinoma

Roshandel, G. and Nouroozi, A. and Pourshams, A. and Amiriani, T. and Semnani, S. and Merat, S. and Khoshnia, M. (2013) Endoscopic screening for esophageal squamous cell carcinoma. Archives of Iranian Medicine, 16 (6). pp. 351-357. ISSN 10292977 (ISSN)

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Abstract

Esophageal cancer (EC) is the eighth common cancer and the sixth most common cause of death from cancer worldwide. Esophageal squamous cell carcinoma (ESCC) remains the most common type of EC in the developing world and an important health problem in high-risk areas. Most of ESCC cases present in late stages, resulting in delayed diagnosis and poor prognosis. Prevention is the most effective strategy to control ESCC. Primary and secondary preventive methods may be considered for ESCC. In primary prevention, we try to avoid known risk factors. The aim of the secondary preventive method (ESCC screening programs) is to detect and eliminate premalignant precursor lesion of ESCC, preventing its progression into advanced stages. Similar to all population-based screening programs, any screening for early detection of ESCC must be cost-effective; otherwise, screening may not be indicated in that population. Endoscopy with iodine staining has been accepted as a population-level ESCC screening program in some high-risk areas including parts of China. This method may be too expensive and invasive in other high-risk communities. Nonendoscopic methods may be more applicable in these populations for population-based screenings. The limitations (questionable validity and costs) of new endoscopic imaging modalities, including narrow-band imaging (NBI), made them inappropriate to be used in population-level ESCC screening programs. Low-cost, less-invasive endoscopic imaging methods with acceptable diagnostic performance may make screening of ESCC in high-risk areas cost-effective.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Arch. Iran. Med. [Field not mapped to EPrints] C2 - 23725069 [Field not mapped to EPrints] AD - Digestive Diseases Research Institute (DDRI), Tehran University of Medical Sciences (TUMS), Tehran, Iran [Field not mapped to EPrints] AD - Golestan Research Center of Gastroenterology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Carcinoma, Endoscopic screening, Esophageal cancer, Iran, Squamous cell carcinoma, iodine, lugol, cancer control, cancer grading, cancer prognosis, cancer screening, chromoendoscopy, confocal laser microscopy, cost effectiveness analysis, diagnostic accuracy, elastic scattering spectroscopy, endocytoscopy, esophageal squamous cell carcinoma, esophagus ulcer, fluorescence imaging, high risk population, human, narrow band imaging, optical coherence tomography, pathogenesis, primary prevention, retrosternal pain, review, secondary prevention, sensitivity and specificity, trimodal imaging, Carcinoma, Squamous Cell, Coloring Agents, Diagnostic Imaging, Early Detection of Cancer, Esophageal Neoplasms, Esophagoscopy, Fluorescence, Humans, Iodine, Iran
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 15 Apr 2015 09:06
Last Modified: 10 May 2015 14:56
URI: http://eprints.goums.ac.ir/id/eprint/1883

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