Golestan University of Medical Sciences Repository

Diabetes mellitus, thyroid dysfunctions and osteoporosis: Is there an association?

Qorbani, M. and Bazrafshan, H.R. and Aghaei, M. and Dashti, H.S. and Rezapour, A. and Asayesh, H. and Mohammadi, R. and Mohammadi, Y. and Ansari, H. and Mansourian, M. (2013) Diabetes mellitus, thyroid dysfunctions and osteoporosis: Is there an association? Journal of Diabetes and Metabolic Disorders, 12 (1). ISSN 22516581 (ISSN)

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Abstract

Background: Osteoporosis is the most common metabolic bone disease with complicated, multifactorial and heterogenic nature that has no known pathological cause. As the role of Diabetes Mellitus (DM) and thyroid dysfunctions in the prevalence of osteoporosis is not exactly known, therefore this study was designed to evaluate the probable association between osteoporosis with DM and thyroid dysfunctions in Iranian patients.Methods: In this cross-sectional study, 300 subjects out of the total number of patients referring to Gorgan bone densitometry centers (3000subjects) were selected via random sampling method in 2009. Individual characteristics, DM, thyroid dysfunctions and densitometry results were collected from densitometry records. Data analysis was carried out by SPSS version 16 software and by using Chi square and T-test. The level of significance in all tests was considered 0.05.Results: The mean of T-score in lumbar and femoral areas of diabetic patients were -0.87 ± 1.08 and -1.94 ± 1.33 and in patient with thyroid dysfunctions was -0.80 ± 1.09 and -1.64 ± 1.24 respectively. The mean of BMD in lumbar and femoral areas of diabetic patients were 0.96 ± 0.19 and 0.75 ± 0.19 and in patient with thyroid dysfunctions were 0.96 ± 0.17 and 0.76 ±0.19 respectively. The mean of BMI in osteoporotic subjects in the lumbar and femoral areas were 25.94 ± 5.62 and 26.95 ± 5.20 respectively. The association between BMI and BMD in the lumbar and femoral areas were statistically significant, but the association between DM and thyroid dysfunctions with BMD and T-score in the femoral and lumbar areas was not statistically significant (P-value > 0.05).Conclusion: The results of current study show that there is no association between DM and thyroid dysfunctions with osteoporosis. © 2013 Qorbani et al.; licensee BioMed Central Ltd.

Item Type: Article
Additional Information: Unmapped bibliographic data: C7 - 38 [EPrints field already has value set] LA - English [Field not mapped to EPrints] J2 - J. Diabetes Metabolic Disord. [Field not mapped to EPrints] AD - Department of Public Health, Alborz University of Medical SciencesKaraj, Iran [Field not mapped to EPrints] AD - Non-Communicable Diseases Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical SciencesTehran, Iran [Field not mapped to EPrints] AD - Bone joints and oConnective Tissue Research Center, Golestan University of Medical SciencesGorgan, Iran [Field not mapped to EPrints] AD - Hospital Management Research Center, Iran University of Medical SciencesTehran, Iran [Field not mapped to EPrints] AD - Department of Medical Emergency, Qom University of Medical SciencesQom, Iran [Field not mapped to EPrints] AD - Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical SciencesTehran, Iran [Field not mapped to EPrints] AD - Department of Epidemiology and Biostatistics, School of Public Health, Hamadan University of Medical SciencesHamadan, Iran [Field not mapped to EPrints] AD - Health Promotion Research Center, Zahedan University of Medical SciencesZahedan, Iran [Field not mapped to EPrints] AD - Department of Health Education, Ilam University of Medical SciencesIlam, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Bone density, Diabetes mellitus, Osteoporosis, Thyroid diseases, adult, Article, body mass, bone density, clinical evaluation, cross-sectional study, densitometry, diabetes mellitus, disease association, disease predisposition, female, human, major clinical study, male, osteopenia, osteoporosis, scoring system, thyroid disease, underweight
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 19 Apr 2015 05:34
Last Modified: 10 May 2015 14:47
URI: http://eprints.goums.ac.ir/id/eprint/1855

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