Golestan University of Medical Sciences Repository

Liver functional behavior during thyrotoxicosis: A review

Mansourian, A.R. (2013) Liver functional behavior during thyrotoxicosis: A review. Journal of Biological Sciences, 13 (8). pp. 665-678. ISSN 17273048 (ISSN)

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Abstract

Thyroid and liver are among two vital and important organs which are interrelated in health and disease. The cooperation of thyroid and liver is extremely vital for a proper functional behavior for both thyroid and liver. Liver crucial role in the basic metabolic rate, growth and development is due to the liver ability to transfer the thyroid hormone and deliver it to the various organs intracellular due to thyroid hormone transporting system which is mediated by the liver. Thyrotoxicosis defined as the clinical manifestation of hyperthyroidism, a symptom with various adverse effects on the liver, heart, vascular, nervous and gastrointestinal systems. There are many reports demonstrating the negative side effect of hyperthyroidism on liver function tests which occur due to the accompanying clinical manifestation of thyrotoxicosis. In severe form of hyperthyroidism in addition to liver biochemical alteration and elevated liver enzymes, damages to hepatocytes will occur. Therefore it is strongly recommended that subjects with either of hyperthyroid or liver dysfunction should be carefully examined simultaneously for both organs to have a clear cut diagnosis and to assist the patient with proper therapeutically treatments. © 2013 Asian Network for Scientific Information.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - J. Biol. Sci. [Field not mapped to EPrints] AD - Metabolic Disorders Research Center, Gorgan Medical School, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Disease, Liver, Thyroid gland, Thyroid hormones, alanine aminotransferase, alkaline phosphatase, aspartate aminotransferase, beta globulin, bilirubin, gamma glutamyltransferase, high density lipoprotein cholesterol, isocitrate dehydrogenase, liothyronine, low density lipoprotein cholesterol, thyroid hormone receptor, thyroxine, acute on chronic liver failure, article, autoimmunity, gene mutation, Graves disease, human, hyperthyroidism, hypertransaminasemia, liver cirrhosis, liver dysfunction, liver function test, liver metabolism, metabolic rate, prevalence, thyrotoxicosis
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 18 Apr 2015 07:53
Last Modified: 18 Apr 2015 07:53
URI: http://eprints.goums.ac.ir/id/eprint/1807

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