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The association of increased stomach wall radiotracer uptake with prolonged use of Omeprazole capsules on myocardial perfusion imaging (MPI) using 99mTc-sestamibi SPECT

Javadi, H. and Jallalat, S. and Semnani, S. and Mogharrabi, M. and Nabipour, I. and Tabib, S.M. and Abbaszadeh, M. and Assadi, M. (2013) The association of increased stomach wall radiotracer uptake with prolonged use of Omeprazole capsules on myocardial perfusion imaging (MPI) using 99mTc-sestamibi SPECT. Nuclear Medicine Review, 16 (2). pp. 91-94. ISSN 15069680 (ISSN)

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Abstract

Myocardial perfusion imaging (MPI) is widely used in routine practice for diagnosis and risk stratification of coronary artery disease (CAD). Intense curvilinear activity in the stomach wall of a patient was seen on MPI raw data. This phenomenon was completely dissimilar to the familiar intraluminal gastric reflux of sestamibi. This observed activity could have resulted in false-positive or false-negative artifacts - and inaccurate diagnosis - of the inferior wall of the left ventricle after MPI processing. On further exploration, the current researchers found that the patient had a history of 10-year Omeprazole capsule consumption. The authors present this infrequent case of intense stomach uptake to stress the related clinical and diagnostic implications with the aim to stimulate acute awareness of possible, unexpected infringements on image quality that could potentially interfere with accurate interpretation of the data. Copyright © 2013 Via Medica.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Nucl. Med. Rev. [Field not mapped to EPrints] C2 - 24068640 [Field not mapped to EPrints] AD - Golestan Research Center of Gastroenterology and Hepatology (GRCGH), Golestan University of Medical Sciences (GUOMS), Gorgan, Iran [Field not mapped to EPrints] AD - Persian Gulf Tropical and Infectious Diseases Research Centre, Bushehr University of Medical Sciences, Bushehr, Iran [Field not mapped to EPrints] AD - Department of Gastroenterology, School of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran [Field not mapped to EPrints] AD - Persian Gulf Nuclear Medicine Research Center, Bushehr University of Medical Sciences, Boostan 19 Alley, Sangi Street, Bushehr 7533934698, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: 99mTc-sestamibi cardiac SPECT, Gastric wall, Myocardial perfusion imaging, Proton pump inhibitors, dipyridamole, methoxy isobutyl isonitrile technetium tc 99m, milk fat, omeprazole, adult, article, bolus injection, case report, coronary artery disease, coronary risk, drug capsule, drug clearance, drug uptake, electrocardiography monitoring, epigastric discomfort, false negative result, false positive result, female, heart contraction, human, image quality, medical history, middle aged, myocardial perfusion imaging, nausea, questionnaire, risk factor, single photon emission computer tomography, stomach function, stomach wall, stomach wall activity, symptom assessment, thorax pain, Artifacts, Biological Transport, Capsules, Female, Humans, Middle Aged, Myocardial Perfusion Imaging, Omeprazole, Radioactive Tracers, Stomach, Technetium Tc 99m Sestamibi, Time Factors, Tomography, Emission-Computed, Single-Photon
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 19 Apr 2015 06:58
Last Modified: 10 May 2015 06:46
URI: http://eprints.goums.ac.ir/id/eprint/1801

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