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Incidence and predisposing factors of cognitive disorders following off-pump coronary artery bypasses graft surgery

Joudi, M. and Fathi, M. and Harati, H. and Joudi, M. and Izanloo, A. and Rahdari, A. and Soltani, G. (2014) Incidence and predisposing factors of cognitive disorders following off-pump coronary artery bypasses graft surgery. Anesthesiology and Pain Medicine, 4 (4). pp. 1-4. ISSN 22287523 (ISSN)

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Abstract

Patients and Methods: A total of 171 patients who had undergone off-pump CABG without any history of psychiatric disorders were enrolled. Samples were selected according to a purposive sampling method. The Mini-Mental State Examination (MMSE) questionnaire was given to each patients to assess the incidence of cognitive disorder during the first 24 hours of surgery in ICU. To compare creatinine, erythrocytes sedimentation rate, extubation time, and patients’ age between those with and those without postoperative cognitive disorder, independent-samplest test was employed. To compare two groups in terms of any history of diseases such as diabetes, hypertension, and hyperlipidemia, and qualitative C-reactive protein (CRP), Chi square test was used. Results: Results showed that 75% of patients had postoperative cognitive disorder. There was a significant association between the history of hypertension, CRP, and preoperative creatinine levels in both cognitive disorder and control groups. Background: Cognitive disorder, which is a common problem for the hospitalized patients, is a fluctuating cognitive destruction that leads to the loss of consciousness. It is usually accompanied by increased mortality, prolonged hospital stay, and decreased rehabilitation. Objectives: The purpose of this study was to determine the risk factors associated with cognitive disorder after coronary artery bypasses graft surgery (CABG). Conclusions: Given the significant prevalence of postoperative cognitive disorder and significant association between the history of hypertension, CRP, and preoperative creatinine and cognitive disorder, the detection of patient’s clinical symptoms may improve diagnosis, treatment, and even prevention of cognitive disorder. © 2014, Iranian Society of Regional Anesthesia and Pain Medicine (ISRAPM); Published by Kowsar.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - Anesth. Pain Med. [Field not mapped to EPrints] AD - Surgical Oncology Research Center, Mashhad University of Medical SciencesMashhad, Iran [Field not mapped to EPrints] AD - Department of Anesthesiology, Mashhad University of Medical SciencesMashhad, Iran [Field not mapped to EPrints] AD - Department of Neurology, Mashhad University of Medical SciencesMashhad, Iran [Field not mapped to EPrints] AD - Department of Psychiatry, Golestan University of Medical SciencesGorgan, Iran [Field not mapped to EPrints] AD - Department of Radiologic Technology, Mashhad University of Medical SciencesMashhad, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Cognitive disorder, Delirium, Off-pump coronary artery bypass, Risk factors
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 15 Apr 2015 08:54
Last Modified: 24 Feb 2018 08:28
URI: http://eprints.goums.ac.ir/id/eprint/1714

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