Golestan University of Medical Sciences Repository

A review of literature on thyroid hormone disorders originated from extra thyroidal illness

Mansourian, A.R. (2014) A review of literature on thyroid hormone disorders originated from extra thyroidal illness. Journal of Biological Sciences, 14 (1). pp. 20-37. ISSN 17273048 (ISSN)

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Abstract

The definition of non-thyroidal illness arises from the fact that thyroid hormones within blood circulation is reduced not due to the malfunction of thyroid organ, but it is mamifested from disorders of other organs. Clinical conditions such as cardiovascular diseases mainly myocardial infraction, sepsis, surgery and many other chronic and sever diseases are associated with thyroid hormones reduction. Serum T3 concentration is reduced during non-thyroidal illness, but serum T4 concentration is seemed to be raised in most of the cases, which is due to the inhibition of T4 conversion into T3 as result of reduced activity of deidoniase enzyme. It seems the reduction in the T3 concentration do not exhibit neither any negative side effects in metabolism nor any irreversible harm in patient involved. There is not any suggestion that hypothyroidism originated from non-thyroidal illness can be rapidly leads to fatal outcome but such low reduction in thyrod hormones and particularly T3 can be considered as a key factor for the initiating the medical attendance and the necessary steps to prevent further clinical complication. © Asian Network for Scientific Information.

Item Type: Article
Additional Information: Unmapped bibliographic data: LA - English [Field not mapped to EPrints] J2 - J. Biol. Sci. [Field not mapped to EPrints] AD - Department of Biochemistry, Metabolic Disorders Research Center, Gorgan Medical School, Golestan University of Medical Sciences, Gorgan, Iran [Field not mapped to EPrints] DB - Scopus [Field not mapped to EPrints]
Uncontrolled Keywords: Hypothyroidism, Non-thyroid illness, Thyroid gland, Thyroid hormone, thyroid hormone, thyroid hormone receptor, thyroxine binding globulin, thyroxine deiodinase, article, cardiovascular disease, clinical assessment, endocrine disease, hormone substitution, human, hypothalamus hypophysis system, hypothyroidism, liothyronine blood level, metabolism, patient care, thyroid gland, thyroid hormone disorder, thyrotropin blood level, thyroxine blood level
Subjects: مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
موارد کلی
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 18 Apr 2015 07:45
Last Modified: 14 May 2015 10:19
URI: http://eprints.goums.ac.ir/id/eprint/1704

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