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Acute Ischemic Stroke in a 10-Month-Old Baby Recovered with Aspirin

Hosseini, S.A. and Gharib, M.H. and Mirheidari, S.B. and Ghanbarzade, B. and Hosseini, P.S. (2021) Acute Ischemic Stroke in a 10-Month-Old Baby Recovered with Aspirin. Journal of Pediatric Neurology.

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Acute ischemic stroke is rare in children and often brings enduring and permanent morbidity in pediatric population. While there are numerous recommendations for initial treatment, evidence on effectiveness of different therapies among children is limited. Here, we describe a 10-month-old boy who presented with fever, restlessness, seizure and postictal left limb weakness. Examination revealed left hemiplegia and hemiparesthesia. Computed tomography (CT) head showed loss of gray-white matter distinction with diffuse hypodensity in the right temporoparietal lobes and right caudate nucleus. Magnetic resonance imaging (MRI) brain demonstrated diffusion restriction in favor of acute ischemic stroke in the right middle cerebral artery (MCA) territory. Brain MR angiography (MRA) demonstrated complete occlusion of proximal aspect of M1 segment of right MCA. Genetic testing determined a homozygous 4G/4G polymorphism of the PAI-1 gene. Antiplatelet therapy was started after diagnosis and continued for 8 days with antibiotic therapy. Stroke in children and infants is an infrequent condition associated with substantial morbidity and mortality that needs clinicians' care. This case highlights the significance of awareness about stroke in children and emphasizes on further research to compile evidence-based guidelines for acute stroke therapy in children. © 2021 CSIRO. All rights reserved.

Item Type: Article
Additional Information: cited By 0
Subjects: سیستم عصبی WL
سیستم قلب وعروق WG
بیماریهای کودکانWS
فارماکولوژی QV
> دانشکده داروسازی > فارماکولوژی QV

مقالات نمایه شده محققین دانشگاه در سایت ,Web of Science ,Scopus
Divisions: معاونت تحقیقات و فناوری
Depositing User: GOUMS
Date Deposited: 03 Mar 2021 09:08
Last Modified: 03 Mar 2021 09:08
URI: http://eprints.goums.ac.ir/id/eprint/10984

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